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Date: 30-Jan-2025 Category: Not Applicable State: Union Government Country: Europe

Commission Implementing Regulation (EU) 2025/151 of 29 January 2025 concerning the renewal of the authorisation of a preparation of Levilactobacillus brevis DSM 21982 as a feed additive for all animal species and repealing Implementing Regulation (EU) No 838/2012

Issued by European Commission · Directorate-General for Health and Food Safety

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Executive Summary & Key Takeaways

What it means

  • Commission Implementing Regulation (EU) 2025/151 renews the authorization of Levilactobacillus brevis DSM 21982 as a feed additive for all animal species. It classifies the additive as a 'technological additive' within the functional group of 'silage additives'. It also repeals Implementing Regulation (EU) No 838/2012, which previously authorized this feed additive.

Key Changes

  • The authorization of Levilactobacillus brevis DSM 21982 as a feed additive is renewed for 10 years, expiring on 19 February 2035.
  • The additive is classified as a 'technological additive' and belongs to the functional group 'silage additives'.
  • Implementing Regulation (EU) No 838/2012 is repealed.
  • Businesses must establish operational procedures and organizational measures to address potential risks to users of the additive and premixtures. If these risks cannot be eliminated, personal protective equipment (skin, eye, and breathing) must be used.
  • Products produced and labelled before 19 February 2026, according to the previous rules, can continue to be placed on the market and used until existing stocks are exhausted.
  • The minimum dose of the additive when not used in combination with other micro-organisms as silage additives is 1 x 108 CFU/kg fresh material.

Impact Analysis

Feed Additive Manufacturers/Suppliers

  • Suggested Action: Review current product labels and safety protocols, update documentation, and train staff on the new requirements. Ensure that risk mitigation measures are in place for users of the additive.

Animal Feed Producers

  • Suggested Action: Verify that feed formulations and production processes align with the new regulation. Update supplier agreements to ensure compliance.

Farmers/Animal Owners

  • Suggested Action: Review product labels and safety data sheets. Implement appropriate safety measures during handling and use of the additive.

Regulatory Bodies

  • Suggested Action: Update guidance documents and conduct inspections to ensure compliance with the new regulation.

Key Entities Referenced

European Commission: The governing body that adopted this implementing regulation. Levilactobacillus brevis DSM 21982: The feed additive that is the subject of this regulation. Regulation (EC) No 1831/2003: The European Parliament and Council regulation on additives for use in animal nutrition. Implementing Regulation (EU) No 838/2012: The previous regulation authorizing Lactobacillus brevis (DSMZ 21982) as a feed additive, which is now repealed. European Food Safety Authority (EFSA): The authority that provided the scientific opinion on the safety and efficacy of Levilactobacillus brevis DSM 21982. Commission Regulation (EC) No 378/2005: Regulation detailing rules for the implementation of Regulation (EC) No 1831/2003 regarding the duties and tasks of the Community Reference Laboratory. Reference Laboratory: Laboratory set up by Regulation (EC) No 1831/2003 responsible for the method of analysis of the preparation of Levilactobacillus brevis DSM 21982. Standing Committee on Plants, Animals, Food and Feed: Committee that provided an opinion on the measures provided for in this Regulation.
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Official Journal EN of the European Union L series 2025/151 30.1.2025 COMMISSION IMPLEMENTING REGULATION (EU) 2025/151 of 29 January 2025 concerning the renewal of the authorisation of a preparation of Levilactobacillus brevis DSM 21982 as a feed additive for all animal species and repealing Implementing Regulation (EU) No 838/2012 (Text with EEA relevance) THE EUROPEAN COMMISSION, Having regard to the Treaty on the Functioning of the European Union, Having regard to Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003on additives for use in animal nutrition(1), and in particular Article 9(2) thereof, Whereas: (1) Regulation (EC) No 1831/2003 provides for the authorisation of additives for use in animal nutrition and for the grounds and procedures for granting and renewing such authorisation. (2) The preparation of Levilactobacillus brevis DSM 21982 (previously identified as Lactobacillus brevis DSMZ 21982) was authorised for a period of 10 years as a feed additive for all animal species by Commission Implementing Regulation (EU) No 838/2012(2). (3) In accordance with Article 14(1) of Regulation (EC) No 1831/2003, an application was submitted for the renewal of the authorisation of the preparation of Levilactobacillus brevis DSM 21982 as a feed additive for all animal species, requesting the additive to be classified in the additive category ‘technological additives’ and in the functional group ‘silage additives’. That application was accompanied by the particulars and documents required under Article 14(2) of Regulation (EC) No 1831/2003. (4) The European Food Safety Authority (‘the Authority’) concluded in its opinion of 12 March 2024(3) that the preparation of Levilactobacillus brevis DSM 21982 remains safe for all target animal species, the consumers and the environment under the conditions of use currently authorised. The Authority also concluded that the additive should be considered as a potential skin and respiratory sensitizer and any exposure through skin and respiratory tract is considered a risk and stated that it cannot conclude on the eye irritation potential of the additive. The Authority also indicated that there is no need for assessing the efficacy of the additive as the application for renewal of its authorisation does not include a proposal for amending or supplementing the conditions of the original authorisation which would have an impact on the efficacy of the additive. (5) The Reference Laboratory set up by Regulation (EC) No 1831/2003 considered that the conclusions and recommendations reached in the assessment carried out regarding the method of analysis of the preparation of Levilactobacillus brevis DSM 21982 as a feed additive in the context of the previous authorisation are valid and applicable for the current application. In accordance with Article 5(4), point (c), of Commission Regulation (EC) No 378/2005(4), an evaluation report of the Reference Laboratory is therefore not required. (1) OJ L 268, 18.10.2003, p. 29, ELI: http://data.europa.eu/eli/reg/2003/1831/oj. (2) Commission Implementing Regulation (EU) No 838/2012 of 18 September 2012 concerning the authorisation of Lactobacillus brevis (DSMZ 21982) as a feed additive for all animal species (OJ L 252, 19.9.2012, p. 9, ELI: http://data.europa.eu/eli/reg_impl/2012/ 838/oj). (3) EFSA Journal, 22(4), e8725. (4) Commission Regulation (EC) No 378/2005 of 4 March 2005 on detailed rules for the implementation of Regulation (EC) No 1831/2003 of the European Parliament and of the Council as regards the duties and tasks of the Community Reference Laboratory concerning applications for authorisations of feed additives (OJ L 59, 5.3.2005, p. 8, ELI: http://data.europa.eu/eli/reg/ 2005/378/oj). ELI: http://data.europa.eu/eli/reg_impl/2025/151/oj 1/3EN OJ L, 30.1.2025 (6) In view of the above, the Commission considers that the preparation of Levilactobacillus brevis DSM 21982 satisfies the conditions, as provided for in Article 5 of Regulation (EC) No 1831/2003. Accordingly, the authorisation of that additive should be renewed. In addition, the Commission considers that appropriate protective measures should be taken to prevent adverse effects on the health of the users of the additive. Those protective measures should be without prejudice to other workers’ safety requirements under Union law. (7) As a consequence of the renewal of the authorisation of the preparation of Levilactobacillus brevis DSM 21982 as a feed additive, Implementing Regulation (EU) No 838/2012 should be repealed. (8) Since safety reasons do not require the immediate application of the modifications to the conditions of authorisation of the preparation of Levilactobacillus brevis DSM 21982, it is appropriate to provide for a transitional period for interested parties to prepare themselves to meet the new requirements resulting from the renewal of the authorisation. (9) The measures provided for in this Regulation are in accordance with the opinion of the Standing Committee on Plants, Animals, Food and Feed, HAS ADOPTED THIS REGULATION: Article 1 Renewal of the authorisation The authorisation of the preparation specified in the Annex, belonging to the additive category ‘technological additives’ and to the functional group ‘silage additives’, is renewed subject to the conditions laid down in that Annex. Article 2 Repeal of Implementing Regulation (EU) No 838/2012 Implementing Regulation (EU) No 838/2012 is repealed. Article 3 Transitional measures The preparation specified in the Annex and feed containing it, which are produced and labelled before 19 February 2026in accordance with the rules applicable before 19 February 2025may continue to be placed on the market and used until the existing stocks are exhausted. Article 4 Entry into force This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union. This Regulation shall be binding in its entirety and directly applicable in all Member States. Done at Brussels, 29 January 2025. For the Commission The President Ursula VON DER LEYEN 2/3 ELI: http://data.europa.eu/eli/reg_impl/2025/151/ojANNEX Minimum Maximum Identification Species or Composition, chemical formula, Maximum content content End of period of number of the Additive category Other provisions description, analytical method age authorisation feed additive of animal CFU/kg of fresh material Category: technological additives. Functional group: silage additives 1k20715 Levilactobacillus Additive composition All — — — 1. In the directions for use of the 19 February brevis DSM Preparation of Levilactobacillus brevis animal additive and premixtures, the 2035 21982 DSM 21982 containing a minimum of species storage conditions shall be 8 × 1010 CFU/g additive indicated. Solid form 2. Minimum dose of the additive when it is not used in ———————————— combination with other micro- organisms as silage additives: 1 × Characterisation of the active substance 108 CFU/kg fresh material. Viable cells of Levilactobacillus brevis DSM 21982 3. For users of the additive and premixtures, feed business ———————————— operators shall establish Analytical method(1) operational procedures and Enumeration in the feed additive of organisational measures to Levilactobacillus brevis DSM 21982: address potential risks resulting from their use. Where those risks — Spread plate method on MRS agar cannot be eliminated by such (EN 15787) procedures and measures, the additive and premixtures shall be Identification of Levilactobacillus brevis used with personal skin, eye and DSM 21982: breathing protective equipment. — Pulsed Field Gel Electrophoresis (PFGE) – CEN/TS 17697 or DNA sequencing methods (1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa- evaluation-reports_en. ELI: http://data.europa.eu/eli/reg_impl/2025/151/oj 3/3 OJ L, 30.1.2025 EN

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