See Full Document Text
Official Journal EN
of the European Union L series
2025/157 30.1.2025
COMMISSION IMPLEMENTING REGULATION (EU) 2025/157
of 29 January 2025
concerning the authorisation of microcrystalline cellulose, methyl cellulose, ethyl cellulose,
hydroxypropyl cellulose, hydroxypropyl methyl cellulose and sodium carboxymethyl cellulose as
feed additives for all animal species
(Text with EEA relevance)
THE EUROPEAN COMMISSION,
Having regard to the Treaty on the Functioning of the European Union,
Having regard to Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003on
additives for use in animal nutrition(1), and in particular Article 9(2) thereof,
Whereas:
(1) Regulation (EC) No 1831/2003 provides for the authorisation of additives for use in animal nutrition and for the
grounds and procedures for granting such an authorisation. Article 10(2) of that Regulation provides for the
re-evaluation of additives authorised pursuant to Council Directive 70/524/EEC(2).
(2) The substances microcrystalline cellulose, methyl cellulose, ethyl cellulose, hydroxypropyl cellulose, hydroxypropyl
methyl cellulose and sodium carboxymethyl cellulose were authorised without a time limit pursuant to
Directive 70/524/EEC as feed additives for all animal species. Those substances were subsequently entered in the
Register of Feed Additives as existing products, in accordance with Article 10(1), point (b), of Regulation (EC)
No 1831/2003.
(3) In accordance with Article 10(2) of Regulation (EC) No 1831/2003 in conjunction with Article 7 thereof,
applications were submitted for the re-evaluation of microcrystalline cellulose, methyl cellulose, ethyl cellulose,
hydroxypropyl cellulose, hydroxypropyl methyl cellulose and sodium carboxymethyl cellulose as feed additives for
all animal species. The applicants requested microcrystalline cellulose, methyl cellulose, hydroxypropyl methyl
cellulose and sodium carboxymethyl cellulose to be classified in the additive category ‘technological additives’ and
in the functional groups ‘emulsifiers’, ‘stabilisers’, ‘thickeners’ and ‘gelling agents’; ethyl cellulose in the additive
category ‘technological additives’ and in the functional group ‘stabilisers’ and hydroxypropyl cellulose in the additive
category ‘technological additives’ and in the functional groups ‘emulsifiers’, ‘stabilisers’, ‘thickeners’ and ‘gelling
agents’. The applications were accompanied by the particulars and documents required under Article 7(3) of
Regulation (EC) No 1831/2003.
(4) In addition, in accordance with Article 7 of Regulation (EC) No 1831/2003, applications were submitted for the
authorisation of microcrystalline cellulose, methyl cellulose, hydroxypropyl methyl cellulose and sodium
carboxymethyl cellulose as feed additives for all animal species, requesting them to be classified in the additive
category ‘technological additives’ and in the functional group ‘binders’. Those applications were accompanied by the
particulars and documents required under Article 7(3) of Regulation (EC) No 1831/2003.
(1) OJ L 268, 18.10.2003, p. 29, ELI: https://eur-lex.europa.eu/eli/reg/2003/1831/oj.
(2) Council Directive 70/524/EEC of 23 November 1970 concerning additives in feedingstuffs (OJ L 270, 14.12.1970, p. 1, ELI: http://
data.europa.eu/eli/dir/1970/524/oj).
ELI: http://data.europa.eu/eli/reg_impl/2025/157/oj 1/41EN
OJ L, 30.1.2025
(5) The European Food Safety Authority (‘the Authority’) concluded in its opinions of 2 July 2020(3) and 31 January
2024(4) that, under the proposed conditions of use, microcrystalline cellulose, methyl cellulose, ethyl cellulose,
hydroxypropyl cellulose, hydroxypropyl methyl cellulose and sodium carboxymethyl cellulose, are safe for all
animal species, the consumer and the environment. In the absence of data, it was not in the position to conclude on
the safety for the user. No specific data on the efficacy of these additives in feedingstuffs were provided, but as they
are all authorised for use as food additives, the Authority concluded that the effect seen when those substances are
used in food could reasonably be expected to be seen when they are used as additives in feed. It also verified the
reports on the method of analysis of the feed additives in feed submitted by the Reference Laboratory set up by
Regulation (EC) No 1831/2003.
(6) In view of the above, the Commission considers that microcrystalline cellulose, methyl cellulose, ethyl cellulose,
hydroxypropyl cellulose, hydroxypropyl methyl cellulose and sodium carboxymethyl cellulose satisfy the conditions
provided for in Article 5 of Regulation (EC) No 1831/2003. Accordingly, the use of those substances should be
authorised. In addition, the Commission considers that appropriate protective measures should be taken to prevent
adverse effects on the health of the users of the additives.
(7) Since safety reasons do not require the immediate application of the modifications to the conditions of authorisation
of the substances concerned, as far as they belong to the functional groups ‘emulsifiers’, ‘stabilisers’, ‘thickeners’ and
‘gelling agents’, it is appropriate to provide for a transitional period for interested parties to prepare themselves to
meet the new requirements resulting from the authorisation.
(8) The measures provided for in this Regulation are in accordance with the opinion of the Standing Committee on
Plants, Animals, Food and Feed,
HAS ADOPTED THIS REGULATION:
Article 1
Authorisation
The substances specified in the Annex, belonging to the additive category ‘technological additives’ and the functional
groups ‘emulsifiers’, ‘stabilisers’, ‘thickeners’, ‘gelling agents’ or ‘binders’, are authorised as additives in animal nutrition,
subject to the conditions laid down in that Annex.
Article 2
Transitional measures
1. The feed additives microcrystalline cellulose, methyl cellulose, ethyl cellulose, hydroxypropyl cellulose,
hydroxypropyl methyl cellulose and sodium carboxymethyl cellulose, as authorised pursuant to Directive 70/524/EEC and
premixtures containing these additives, which are produced and labelled before 19 August 2025 in accordance with the
rules applicable before 19 February 2025may continue to be placed on the market and used until the stocks concerned
are exhausted.
2. Compound feed and feed materials containing the feed additives referred to in paragraph 1, which are produced and
labelled before 19 February 2026 in accordance with the rules applicable before 19 February 2025 may continue to be
placed on the market and used until the stocks concerned are exhausted if they are intended for food-producing animals.
(3) EFSA Journal 2020;18(7):6209; EFSA Journal 2020;18(7):6212; EFSA Journal 2020;18(7):6210; EFSA Journal 2020;18(7):6213; EFSA
Journal 2020;18(7):6234; EFSA Journal 2020;18(7):6211.
(4) EFSA Journal 2024;22:e8625; EFSA Journal 2024;22:e8637; EFSA Journal 2024;22:e8636; EFSA Journal 2024;22:e8626.
2/41 ELI: http://data.europa.eu/eli/reg_impl/2025/157/ojEN
OJ L, 30.1.2025
3. Compound feed and feed materials containing the feed additives referred to in paragraph 1, which are produced and
labelled before 19 February 2027 in accordance with the rules applicable before 19 February 2025 may continue to be
placed on the market and used until the stocks concerned are exhausted if they are intended for non-food producing
animals.
Article 3
Entry into force
This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the
European Union.
This Regulation shall be binding in its entirety and directly applicable in all Member States.
Done at Brussels, 29 January 2025.
For the Commission
The President
Ursula VON DER LEYEN
ELI: http://data.europa.eu/eli/reg_impl/2025/157/oj 3/41ANNEX
Minimum Maximum
Identifica- content content
Species or
tion number Composition, chemical formula, description, Maximum End of period of
Additive category Other provisions
of the feed analytical method age mg of additive/kg of complete authorisation
of animal
additive feedingstuff with a moisture
content of 12 %
Category: technological additives. Functional group: emulsifiers
1c460i Microcrystalline Additive composition All - - - 1. In the directions for use of 19 February
cellulose Microcrystalline cellulose ≥ 97 % animal the additive and 2035
(calculated as cellulose on the anhydrous species premixtures, the storage
basis) conditions and the stability
to heat treatment shall be
Solid form indicated.
Characterisation of the active substance 2. For users of the additive and
Microcrystalline cellulose ≥ 97 % premixtures, feed business
(calculated as cellulose on the anhydrous operators shall establish
basis), manufactured from wood pulp operational procedures and
partially depolymerised with a organisational measures to
hydrolysation process obtained with address potential risks
heat and mineral acid resulting from their use.
Where those risks cannot be
CAS No: 9004-34-6
eliminated by such
Loss on drying: ≤ 7 % procedures and measures,
the additive and premixtures
Water-soluble matters: ≤ 0,24 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Starch: not detectable
Carboxyl groups ≤ 1 %
Particle size: ≤ 10 % of particles of less
than 5 μm
4/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica- content content Species or
tion number Composition, chemical formula, description, Maximum End of period of
Additive category Other provisions
of the feed analytical method age mg of additive/kg of complete authorisation
of animal
additive feedingstuff with a moisture
content of 12 %
Analytical method(1)
For the identification/characterisation of
microcrystalline cellulose in the feed
additive:
— Commission Regulation (EU)
No 231/2012(2)for
microcrystalline cellulose and the
corresponding methods of the FAO
JECFA ‘microcrystalline cellulose’
monograph and the ‘Volume 4’ of
FAO JECFA combined compendium
for food additives specifications
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
(2) Commission Regulation (EU) No 231/2012 of 9 March 2012laying down specifications for food additives listed in Annexes II and III to Regulation (EC) No 1333/2008 of the European Parliament and of the
Council (OJ L 83, 22.3.2012, p. 1, ELI: http://data.europa.eu/eli/reg/2012/231/oj).
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
5/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: stabilisers
1c460i Microcrystalline Additive composition All - - - 1. In the directions for use of 19 February
cellulose Microcrystalline cellulose ≥ 97 % animal the additive and 2035
(calculated as cellulose on the anhydrous species premixtures, the storage
basis) conditions and the stability
to heat treatment shall be
Solid form indicated.
Characterisation of the active substance 2. For users of the additive and
Microcrystalline cellulose ≥ 97 % premixtures, feed business
(calculated as cellulose on the anhydrous operators shall establish
basis), manufactured from wood pulp operational procedures and
partially depolymerised with a organisational measures to
hydrolysation process obtained with address potential risks
heat and mineral acid resulting from their use.
Where those risks cannot be
CAS No: 9004-34-6
eliminated by such
Loss on drying: ≤ 7 % procedures and measures,
the additive and premixtures
Water-soluble matters: ≤ 0,24 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Carboxyl groups ≤ 1 %
Particle size: ≤ 10 % of particles of less
than 5 μm
Analytical method(1)
For the identification/characterisation of
microcrystalline cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
microcrystalline cellulose and the
corresponding methods of the FAO
6/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
JECFA ‘microcrystalline cellulose’
monograph and the ‘Volume 4’ of
FAO JECFA combined compendium
for food additives specifications
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: thickeners
1c460i Microcrystalline Additive composition All - - - 1. In the directions for use of 19 February
cellulose Microcrystalline cellulose ≥ 97 % animal the additive and 2035
(calculated as cellulose on the anhydrous species premixtures, the storage
basis) conditions and the stability
to heat treatment shall be
Solid form indicated.
Characterisation of the active substance 2. For users of the additive and
Microcrystalline cellulose ≥ 97 % premixtures, feed business
(calculated as cellulose on the anhydrous operators shall establish
basis), manufactured from wood pulp operational procedures and
partially depolymerised with a organisational measures to
hydrolysation process obtained with address potential risks
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
7/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
heat and mineral acid resulting from their use.
Where those risks cannot be
CAS No: 9004-34-6
eliminated by such
Loss on drying: ≤ 7 % procedures and measures,
the additive and premixtures
Water-soluble matters: ≤ 0,24 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Carboxyl groups ≤ 1 %
Particle size: ≤ 10 % of particles of less
than 5 μm
Analytical method(1)
For the identification/characterisation of
microcrystalline cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
microcrystalline cellulose and the
corresponding methods of the FAO
JECFA ‘microcrystalline cellulose’
monograph and the ‘Volume 4’ of
FAO JECFA combined compendium
for food additives specifications
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
8/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: gelling agents
1c460i Microcrystalline Additive composition All - - - 1. In the directions for use of 19 February
cellulose Microcrystalline cellulose ≥ 97 % animal the additive and 2035
(calculated as cellulose on the anhydrous species premixtures, the storage
basis) conditions and the stability
to heat treatment shall be
Solid form indicated.
Characterisation of the active substance 2. For users of the additive and
Microcrystalline cellulose ≥ 97 % premixtures, feed business
(calculated as cellulose on the anhydrous operators shall establish
basis), manufactured from wood pulp operational procedures and
partially depolymerised with a organisational measures to
hydrolysation process obtained with address potential risks
heat and mineral acid resulting from their use.
Where those risks cannot be
CAS No: 9004-34-6
eliminated by such
Loss on drying: ≤ 7 % procedures and measures,
the additive and premixtures
Water-soluble matters: ≤ 0,24 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Carboxyl groups ≤ 1 %
Particle size: ≤ 10 % of particles of less
than 5 μm
Analytical method(1)
For the identification/characterisation of
microcrystalline cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
microcrystalline cellulose and the
corresponding methods of the FAO
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
9/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
JECFA ‘microcrystalline cellulose’
monograph and the ‘Volume 4’ of
FAO JECFA combined compendium
for food additives specifications
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: binders
1c460i Microcrystalline Additive composition All - - - 1. In the directions for use of 19 February
cellulose Microcrystalline cellulose ≥ 97 % animal the additive and 2035
(calculated as cellulose on the anhydrous species premixtures, the storage
basis) conditions and the stability
to heat treatment shall be
Solid form indicated.
Characterisation of the active substance 2. For users of the additive and
Microcrystalline cellulose ≥ 97 % premixtures, feed business
(calculated as cellulose on the anhydrous operators shall establish
basis), manufactured from wood pulp operational procedures and
10/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
partially depolymerised with a organisational measures to
hydrolysation process obtained with address potential risks
heat and mineral acid resulting from their use.
Where those risks cannot be
CAS No: 9004-34-6
eliminated by such
Loss on drying: ≤ 7 % procedures and measures,
the additive and premixtures
Water-soluble matters: ≤ 0,24 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Carboxyl groups ≤ 1 %
Particle size: ≤ 10 % of particles of less
than 5 μm
Analytical method(1)
For the identification/characterisation of
microcrystalline cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
microcrystalline cellulose and the
corresponding methods of the FAO
JECFA ‘microcrystalline cellulose’
monograph and the ‘Volume 4’ of
FAO JECFA combined compendium
for food additives specifications
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
11/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: emulsifiers
1c461 Methyl cellulose Additive composition All - - - 1. In the directions for use of 19 February
Methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Methyl cellulose obtained from wood
pulp or cotton by treatment with alkali 2. For users of the additive and
and methylation of the alkali cellulose premixtures, feed business
with methyl chloride operators shall establish
operational procedures and
CAS No: 9004-67-5
organisational measures to
Content not less than 25 % and not more address potential risks
than 33 % of methoxyl groups (-OCH ) resulting from their use.
3
and not more than 5 % of Where those risks cannot be
hydroxyethoxyl groups (-OCH CH OH) eliminated by such
2 2
procedures and measures,
Loss on drying: ≤ 10 %
the additive and premixtures
Sulfated ash: ≤ 1,5 % shall be used with personal
skin, eye and breathing
Analytical method(1) protective equipment.
For the identification/characterisation of
methyl cellulose in the feed additive:
— Regulation (EU) No 231/2012 for
methyl cellulose and the
corresponding methods of the FAO
JECFA ‘Methyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
12/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
food additives specifications and the
European Pharmacopoeia
monograph 0345
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: stabilisers
1c461 Methyl cellulose Additive composition All - - - 1. In the directions for use of 19 February
Methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Methyl cellulose obtained from wood
pulp or cotton by treatment with alkali 2. For users of the additive and
and methylation of the alkali cellulose premixtures, feed business
with methyl chloride operators shall establish
operational procedures and
CAS No: 9004-67-5
organisational measures to
Content not less than 25 % and not more address potential risks
than 33 % of methoxyl groups (-OCH ) resulting from their use.
3
Where those risks cannot be
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
13/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
and not more than 5 % of eliminated by such
hydroxyethoxyl groups (-OCH CH OH) procedures and measures,
2 2
the additive and premixtures
Loss on drying: ≤ 10 %
shall be used with personal
Sulfated ash: ≤ 1,5 % skin, eye and breathing
protective equipment.
Analytical method(1)
For the identification/characterisation of
methyl cellulose in the feed additive:
— Regulation (EU) No 231/2012 for
methyl cellulose and the
corresponding methods of the FAO
JECFA ‘Methyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
food additives specifications and the
European Pharmacopoeia
monograph 0345
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
14/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: thickeners
1c461 Methyl cellulose Additive composition All - - - 1. In the directions for use of 19 February
Methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Methyl cellulose obtained from wood
pulp or cotton by treatment with alkali 2. For users of the additive and
and methylation of the alkali cellulose premixtures, feed business
with methyl chloride operators shall establish
operational procedures and
CAS No: 9004-67-5
organisational measures to
Content not less than 25 % and not more address potential risks
than 33 % of methoxyl groups (-OCH ) resulting from their use.
3
and not more than 5 % of Where those risks cannot be
hydroxyethoxyl groups (-OCH CH OH) eliminated by such
2 2
procedures and measures,
Loss on drying: ≤ 10 %
the additive and premixtures
Sulfated ash: ≤ 1,5 % shall be used with personal
skin, eye and breathing
Analytical method(1) protective equipment.
For the identification/characterisation of
methyl cellulose in the feed additive:
— Regulation (EU) No 231/2012 for
methyl cellulose and the
corresponding methods of the FAO
JECFA ‘Methyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
15/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
food additives specifications and the
European Pharmacopoeia
monograph 0345
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: gelling agents
1c461 Methyl cellulose Additive composition All - - - 1. In the directions for use of 19 February
Methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Methyl cellulose obtained from wood
pulp or cotton by treatment with alkali 2. For users of the additive and
and methylation of the alkali cellulose premixtures, feed business
with methyl chloride operators shall establish
operational procedures and
CAS No: 9004-67-5
organisational measures to
address potential risks
16/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Content not less than 25 % and not more resulting from their use.
than 33 % of methoxyl groups (-OCH ) Where those risks cannot be
3
and not more than 5 % of eliminated by such
hydroxyethoxyl groups (-OCH CH OH) procedures and measures,
2 2
the additive and premixtures
Loss on drying: ≤ 10 %
shall be used with personal
Sulfated ash: ≤ 1,5 % skin, eye and breathing
protective equipment.
Analytical method(1)
For the identification/characterisation of
methyl cellulose in the feed additive:
— Regulation (EU) No 231/2012 for
methyl cellulose and the
corresponding methods of the FAO
JECFA ‘Methyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
food additives specifications and the
European Pharmacopoeia
monograph 0345
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
17/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: binders
1c461 Methyl cellulose Additive composition All - - - 1. In the directions for use of 19 February
Methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Methyl cellulose obtained from wood
pulp or cotton by treatment with alkali 2. For users of the additive and
and methylation of the alkali cellulose premixtures, feed business
with methyl chloride operators shall establish
operational procedures and
CAS No: 9004-67-5
organisational measures to
Content not less than 25 % and not more address potential risks
than 33 % of methoxyl groups (-OCH ) resulting from their use.
3
and not more than 5 % of Where those risks cannot be
hydroxyethoxyl groups (-OCH CH OH) eliminated by such
2 2
procedures and measures,
Loss on drying: ≤ 10 %
the additive and premixtures
Sulfated ash: ≤ 1,5 % shall be used with personal
skin, eye and breathing
Analytical method(1) protective equipment.
For the identification/characterisation of
methyl cellulose in the feed additive:
— Regulation (EU) No 231/2012 for
methyl cellulose and the
corresponding methods of the FAO
JECFA ‘Methyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
18/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
food additives specifications and the
European Pharmacopoeia
monograph 0345
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: stabilisers
1d462 Ethyl cellulose Additive composition All - - - 1. In the directions for use of 19 February
Ethyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Ethyl cellulose, obtained by reaction of
partially depolymerised cellulose with 2. For users of the additive and
ethyl chloride premixtures, feed business
operators shall establish
Ethoxyl groups (-OC H ): > 44 % and <
2 5 operational procedures and
50 % on the dried basis (equivalent to not
organisational measures to
more than 2,6 ethoxyl groups per
address potential risks
resulting from their use.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
19/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
anhydroglucose unit) Where those risks cannot be
eliminated by such
CAS No: 9004-57-3
procedures and measures,
Loss on drying: ≤ 3% the additive and premixtures
shall be used with personal
Sulfated ash: ≤ 0,4 %
skin, eye and breathing
Analytical method(1) protective equipment.
For the identification/characterisation of
ethyl cellulose in the feed additive:
— Regulation (EU) No 231/2012 for
ethyl cellulose and the
corresponding methods described
in the FAO JECFA ‘Ethyl cellulose’
monograph and the European
Pharmacopoeia monograph 0822
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
20/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: emulsifiers
1c463 Hydroxypropyl Additive composition All animal - - - 1. In the directions for use of 19 February
cellulose Hydroxypropyl cellulose species the additive and 2035
premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl cellulose, obtained by
partial etherification of cellulose from 2. For users of the additive and
fibrous plant material with hydroxypropyl premixtures, feed business
groups operators shall establish
operational procedures and
Hydroxypropoxyl groups
organisational measures to
(-OCH CHOHCH ): ≤ 80,5 % equivalent to
2 3 address potential risks
not more than 4,6 hydroxypropyl groups
resulting from their use.
per anhydroglucose unit on the anhydrous
Where those risks cannot be
basis
eliminated by such
CAS No: 9004-64-2 procedures and measures,
the additive and premixtures
Loss on drying: ≤ 10 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Propylene chlorohydrins ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl cellulose and the
corresponding methods of FAO
JECFA ‘hydroxypropyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
21/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
food additives specifications and the
European Pharmacopeia monograph
0337
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: stabilisers
1c463 Hydroxypropyl Additive composition All animal - - - 1. In the directions for use of 19 February
cellulose Hydroxypropyl cellulose species the additive and 2035
premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl cellulose, obtained by
partial etherification of cellulose from 2. For users of the additive and
fibrous plant material with hydroxypropyl premixtures, feed business
groups operators shall establish
operational procedures and
Hydroxypropoxyl groups
organisational measures to
(-OCH CHOHCH ): ≤ 80,5 % equivalent to
2 3 address potential risks
not more than 4,6 hydroxypropyl groups
resulting from their use.
Where those risks cannot be
22/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
per anhydroglucose unit on the anhydrous eliminated by such
basis procedures and measures,
the additive and premixtures
CAS No: 9004-64-2
shall be used with personal
Loss on drying: ≤ 10 % skin, eye and breathing
protective equipment.
Sulfated ash: ≤ 0,5 %
Propylene chlorohydrins ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl cellulose and the
corresponding methods of FAO
JECFA ‘hydroxypropyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
food additives specifications and the
European Pharmacopeia monograph
0337
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
23/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: thickeners
1c463 Hydroxypropyl Additive composition All animal - - - 1. In the directions for use of 19 February
cellulose Hydroxypropyl cellulose species the additive and 2035
premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl cellulose, obtained by
partial etherification of cellulose from 2. For users of the additive and
fibrous plant material with hydroxypropyl premixtures, feed business
groups operators shall establish
operational procedures and
Hydroxypropoxyl groups
organisational measures to
(-OCH CHOHCH ): ≤ 80,5 % equivalent to
2 3 address potential risks
not more than 4,6 hydroxypropyl groups
resulting from their use.
per anhydroglucose unit on the anhydrous
Where those risks cannot be
basis
eliminated by such
CAS No: 9004-64-2 procedures and measures,
the additive and premixtures
Loss on drying: ≤ 10 %
shall be used with personal
Sulfated ash: ≤ 0,5 % skin, eye and breathing
protective equipment.
Propylene chlorohydrins ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl cellulose and the
corresponding methods of FAO
JECFA ‘hydroxypropyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
24/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
food additives specifications and the
European Pharmacopeia monograph
0337
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: gelling agents
1c463 Hydroxypropyl Additive composition All animal - - - 1. In the directions for use of 19 February
cellulose Hydroxypropyl cellulose species the additive and 2035
premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl cellulose, obtained by
partial etherification of cellulose from 2. For users of the additive and
fibrous plant material with hydroxypropyl premixtures, feed business
groups operators shall establish
operational procedures and
Hydroxypropoxyl groups
organisational measures to
(-OCH CHOHCH ): ≤ 80,5 % equivalent to
2 3 address potential risks
not more than 4,6 hydroxypropyl groups
resulting from their use.
Where those risks cannot be
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
25/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category of Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed animal
feedingstuff with a moisture
additive
content of 12 %
per anhydroglucose unit on the anhydrous eliminated by such
basis procedures and measures,
the additive and premixtures
CAS No: 9004-64-2
shall be used with personal
Loss on drying: ≤ 10 % skin, eye and breathing
protective equipment.
Sulfated ash: ≤ 0,5 %
Propylene chlorohydrins ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl cellulose and the
corresponding methods of FAO
JECFA ‘hydroxypropyl cellulose’
monograph, the ‘Volume 4’ of FAO
JECFA combined compendium for
food additives specifications and the
European Pharmacopeia monograph
0337
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
26/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica- Species
content content tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of
feedingstuff with a moisture
additive animal
content of 12 %
Category: technological additives. Functional group: emulsifiers
1c464 Hydroxypropyl Additive composition All - - - 1. In the directions for use of 19 February
methyl cellulose Hydroxypropyl methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl methyl cellulose
manufactured reacting partially 2. For users of the additive and
depolymerised cellulose with methyl premixtures, feed business
groups and containing a small degree of operators shall establish
hydroxypropyl substitution operational procedures and
organisational measures to
CAS No: 9004-65-3
address potential risks
Methoxyl groups: (-OCH ) 19-30 % resulting from their use.
3
Where those risks cannot be
Hydroxypropoxyl groups
eliminated by such
(-OCH CHOHCH ): 3-12 %
2 3 procedures and measures,
Loss on drying: ≤ 10 % the additive and premixtures
shall be used with personal
Sulfated ash: ≤ 1,5 % (for products with skin, eye and breathing
viscosity of 50 mPa.s or above); ≤ 3 % (for protective equipment.
products with viscosity below 50 mPa.s)
Propylene chlorohydrins: ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl methyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl methyl cellulose and
the corresponding methods of the
FAO JECFA ‘Hydroxypropyl methyl
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
27/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica- Species
content content
tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of
feedingstuff with a moisture
additive animal
content of 12 %
cellulose’ monograph, the ‘Volume 4’
of FAO JECFA combined
compendium for food additives
specifications and the European
Pharmacopoeia monograph 0348
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica- Species
content content
tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
Category: technological additives. Functional group: stabilisers
1c464 Hydroxypropyl Additive composition All - - - 1. In the directions for use of 19 February
methyl cellulose Hydroxypropyl methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated. Hydroxypropyl methyl cellulose
manufactured reacting partially 2. For users of the additive and
depolymerised cellulose with methyl premixtures, feed business
28/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica- Species
content content tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
groups and containing a small degree of operators shall establish
hydroxypropyl substitution operational procedures and
organisational measures to
CAS No: 9004-65-3
address potential risks
Methoxyl groups (-OCH 3): 19-30 % resulting from their use.
Hydroxypropoxyl groups Where those risks cannot be
(-OCH CHOHCH ): 3-12 % eliminated by such
2 3
procedures and measures,
Loss on drying: ≤ 10 %
the additive and premixtures
Sulfated ash: ≤ 1,5 % (for products with shall be used with personal
viscosity of 50 mPa.s or above); ≤ 3 % (for skin, eye and breathing
products with viscosity below 50 mPa.s) protective equipment.
Propylene chlorohydrins: ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl methyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl methyl cellulose and
the corresponding methods of the
FAO JECFA ‘Hydroxypropyl methyl
cellulose’ monograph, the ‘Volume 4’
of FAO JECFA combined
compendium for food additives
specifications and the European
Pharmacopoeia monograph 0348
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
29/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica- Species
content content
tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
Category: technological additives. Functional group: thickeners
1c464 Hydroxypropyl Additive composition All - - - 1. In the directions for use of 19 February
methyl cellulose Hydroxypropyl methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl methyl cellulose
manufactured reacting partially 2. For users of the additive and
depolymerised cellulose with methyl premixtures, feed business
groups and containing a small degree of operators shall establish
hydroxypropyl substitution operational procedures and
organisational measures to
CAS No: 9004-65-3
address potential risks
Methoxyl groups (-OCH ): 19-30 % resulting from their use.
3
Where those risks cannot be
Hydroxypropoxyl groups
eliminated by such
(-OCH CHOHCH ): 3-12 %
2 3 procedures and measures,
Loss on drying: ≤ 10 % the additive and premixtures
shall be used with personal
Sulfated ash: ≤ 1,5 % (for products with skin, eye and breathing
viscosity of 50 mPa.s or above); ≤ 3 % (for protective equipment.
products with viscosity below 50 mPa.s)
Propylene chlorohydrins: ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl methyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl methyl cellulose and
the corresponding methods of the
FAO JECFA ‘Hydroxypropyl methyl
30/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica- Species
content content tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
cellulose’ monograph, the ‘Volume 4’
of FAO JECFA combined
compendium for food additives
specifications and the European
Pharmacopoeia monograph 0348
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica- Species
content content
tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
Category: technological additives. Functional group: gelling agents
1c464 Hydroxypropyl Additive composition All - - - 1. In the directions for use of 19 February
methyl cellulose Hydroxypropyl methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl methyl cellulose
manufactured reacting partially 2. For users of the additive and
depolymerised cellulose with methyl premixtures, feed business
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
31/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica- Species
content content
tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
groups and containing a small degree of operators shall establish
hydroxypropyl substitution operational procedures and
organisational measures to
CAS No: 9004-65-3
address potential risks
Methoxyl groups (-OCH 3): 19-30 % resulting from their use.
Hydroxypropoxyl groups Where those risks cannot be
(-OCH CHOHCH ): 3-12 % eliminated by such
2 3
procedures and measures,
Loss on drying: ≤ 10 %
the additive and premixtures
Sulfated ash: ≤ 1,5 % (for products with shall be used with personal
viscosity of 50 mPa.s or above); ≤ 3 % (for skin, eye and breathing
products with viscosity below 50 mPa.s) protective equipment.
Propylene chlorohydrins: ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl methyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl methyl cellulose and
the corresponding methods of the
FAO JECFA ‘Hydroxypropyl methyl
cellulose’ monograph, the ‘Volume 4’
of FAO JECFA combined
compendium for food additives
specifications and the European
Pharmacopoeia monograph 0348
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
32/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica- Species
content content tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
Category: technological additives. Functional group: binders
1c464 Hydroxypropyl Additive composition All - - - 1. In the directions for use of 19 February
methyl cellulose Hydroxypropyl methyl cellulose animal the additive and 2035
species premixtures, the storage
Solid form conditions and the stability
to heat treatment shall be
Characterisation of the active substance
indicated.
Hydroxypropyl methyl cellulose 2. For users of the additive and
manufactured reacting partially premixtures, feed business
depolymerised cellulose with methyl operators shall establish
groups and containing a small degree of operational procedures and
hydroxypropyl substitution organisational measures to
address potential risks
CAS No: 9004-65-3
resulting from their use.
Methoxyl groups (-OCH ): 19-30 % Where those risks cannot be
3
eliminated by such
Hydroxypropoxyl groups
procedures and measures,
(-OCH CHOHCH ): 3-12 %
2 3 the additive and premixtures
Loss on drying: ≤ 10 % shall be used with personal
skin, eye and breathing
Sulfated ash: ≤ 1,5 % (for products with
protective equipment.
viscosity of 50 mPa.s or above); ≤ 3 % (for
products with viscosity below 50 mPa.s)
Propylene chlorohydrins: ≤ 0,1 mg/kg
Analytical method(1)
For the identification/characterisation of
hydroxypropyl methyl cellulose in the feed
additive:
— Regulation (EU) No 231/2012 for
hydroxypropyl methyl cellulose and
the corresponding methods of the
FAO JECFA ‘Hydroxypropyl methyl
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
33/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica- Species
content content
tion or
Composition, chemical formula, description, Maximum End of period of
number of Additive cate- Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed gory of
feedingstuff with a moisture
additive animal
content of 12 %
cellulose’ monograph, the ‘Volume 4’
of FAO JECFA combined
compendium for food additives
specifications and the European
Pharmacopoeia monograph 0348
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: emulsifiers
1c466 Sodium Additive composition All - - - 1. In the directions for use of 19 February
carboxymethyl Sodium carboxymethyl cellulose ≥ animal the additive and 2035
cellulose 99,5 % (on the anhydrous basis) species premixtures, the storage
conditions and the stability
Solid form to heat treatment shall be
indicated.
Characterisation of the active substance
Sodium carboxymethyl cellulose ≥ 2. For users of the additive and
99,5 % (on the anhydrous basis), premixtures, feed business
obtained by etherification reaction operators shall establish
operational procedures and
34/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
between the alkali-cellulose complex organisational measures to
and monochloroacetic acid address potential risks
resulting from their use.
CAS No: 9000-32-4
Where those risks cannot be
Carboxymethyl groups (-CH COOH): eliminated by such
2
0,2-1,5 per anhydroglucose unit procedures and measures,
the additive and premixtures
Loss on drying: ≤ 12 %
shall be used with personal
Total glycolate: ≤ 0,4 % (as sodium skin, eye and breathing
glycolate on the anhydrous basis) protective equipment.
Sodium: ≤ 12,4 % (on the anhydrous
basis)
Analytical method(1)
For the identification/characterisation of
sodium carboxymethyl cellulose in the
feed additive:
— Regulation (EU) No 231/2012 for
sodium carboxymethyl cellulose
and the corresponding methods of
FAO JECFA ‘sodium carboxymethyl
cellulose’ monograph and the
‘Volume 4’ of FAO JECFA combined
compendium for food additives
specifications.
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
35/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: stabilisers
1c466 Sodium Additive composition All - - - 1. In the directions for use of 19 February
carboxymethyl Sodium carboxymethyl cellulose ≥ animal the additive and 2035
cellulose 99,5 % (on the anhydrous basis) species premixtures, the storage
conditions and the stability
Solid form to heat treatment shall be
indicated.
Characterisation of the active substance
Sodium carboxymethyl cellulose ≥ 2. For users of the additive and
99,5 % (on the anhydrous basis), premixtures, feed business
obtained by etherification reaction operators shall establish
between the alkali-cellulose complex operational procedures and
and monochloroacetic acid organisational measures to
address potential risks
CAS No: 9000-32-4
resulting from their use.
Carboxymethyl groups (-CH COOH): Where those risks cannot be
2
0,2-1,5 per anydroglucose unit eliminated by such
procedures and measures,
Loss on drying: ≤ 12 %
the additive and premixtures
Total glycolate: ≤ 0,4 % (as sodium shall be used with personal
glycolate on the anhydrous basis) skin, eye and breathing
protective equipment.
Sodium: ≤ 12,4 % (on the anhydrous
basis)
Analytical method(1)
For the identification/characterisation of
sodium carboxymethyl cellulose in the
feed additive:
— Regulation (EU) No 231/2012 for
sodium carboxymethyl cellulose
and the corresponding methods of
FAO JECFA ‘sodium carboxymethyl
36/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
cellulose’ monograph and the
‘Volume 4’ of FAO JECFA combined
compendium for food additives
specifications.
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: thickeners
1c466 Sodium Additive composition All - - - 1. In the directions for use of 19 February
carboxymethyl Sodium carboxymethyl cellulose ≥ animal the additive and 2035
cellulose 99,5 % (on the anhydrous basis) species premixtures, the storage
conditions and the stability
Solid form to heat treatment shall be
indicated.
Characterisation of the active substance
Sodium carboxymethyl cellulose ≥ 2. For users of the additive and
99,5 % (on the anhydrous basis), premixtures, feed business
obtained by etherification reaction operators shall establish
between the alkali-cellulose complex operational procedures and
organisational measures to
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
37/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
and monochloroacetic acid address potential risks
resulting from their use.
CAS No: 9000-32-4
Where those risks cannot be
Carboxymethyl groups (-CH COOH): eliminated by such
2
0,2-1,5 per anydroglucose unit procedures and measures,
the additive and premixtures
Loss on drying: ≤ 12 %
shall be used with personal
Total glycolate: ≤ 0,4 % (as sodium skin, eye and breathing
glycolate on the anhydrous basis) protective equipment.
Sodium: ≤ 12,4 % (on the anhydrous
basis)
Analytical method(1)
For the identification/characterisation of
sodium carboxymethyl cellulose in the
feed additive:
— Regulation (EU) No 231/2012 for
sodium carboxymethyl cellulose
and the corresponding methods of
FAO JECFA ‘sodium carboxymethyl
cellulose’ monograph and the
‘Volume 4’ of FAO JECFA combined
compendium for food additives
specifications.
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
38/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: gelling agents
1c466 Sodium Additive composition All - - - 1. In the directions for use of 19 February
carboxymethyl Sodium carboxymethyl cellulose ≥ animal the additive and 2035
cellulose 99,5 % (on the anhydrous basis) species premixtures, the storage
conditions and the stability
Solid form to heat treatment shall be
indicated.
Characterisation of the active substance
Sodium carboxymethyl cellulose ≥ 2. For users of the additive and
99,5 % (on the anhydrous basis), premixtures, feed business
obtained by etherification reaction operators shall establish
between the alkali-cellulose complex operational procedures and
and monochloroacetic acid organisational measures to
address potential risks
CAS No: 9000-32-4
resulting from their use.
Carboxymethyl groups (-CH COOH): Where those risks cannot be
2
0,2-1,5 per anydroglucose unit eliminated by such
procedures and measures,
Loss on drying: ≤ 12 %
the additive and premixtures
Total glycolate: ≤ 0,4 % (as sodium shall be used with personal
glycolate on the anhydrous basis) skin, eye and breathing
protective equipment.
Sodium: ≤ 12,4 % (on the anhydrous
basis)
Analytical method(1)
For the identification/characterisation of
sodium carboxymethyl cellulose in the
feed additive:
— Regulation (EU) No 231/2012 for
sodium carboxymethyl cellulose
and the corresponding methods of
FAO JECFA ‘sodium carboxymethyl
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
39/41
OJ
L,
30.1.2025
ENMinimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
cellulose’ monograph and the
‘Volume 4’ of FAO JECFA combined
compendium for food additives
specifications.
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
Minimum Maximum
Identifica-
content content
tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
Category: technological additives. Functional group: binders
1c466 Sodium Additive composition All - - - 1. In the directions for use of 19 February
carboxymethyl Sodium carboxymethyl cellulose ≥ animal the additive and 2035
cellulose 99,5 % (on the anhydrous basis) species premixtures, the storage
conditions and the stability
Solid form to heat treatment shall be
indicated.
Characterisation of the active substance
Sodium carboxymethyl cellulose ≥ 2. For users of the additive and
99,5 % (on the anhydrous basis), premixtures, feed business
obtained by etherification reaction operators shall establish
between the alkali-cellulose complex operational procedures and
organisational measures to
40/41
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
EN
OJ
L,
30.1.2025Minimum Maximum
Identifica-
content content tion Species or
Composition, chemical formula, description, Maximum End of period of
number of Additive category Other provisions
analytical method age mg of additive/kg of complete authorisation
the feed of animal
feedingstuff with a moisture
additive
content of 12 %
and monochloroacetic acid address potential risks
resulting from their use.
CAS No: 9000-32-4
Where those risks cannot be
Carboxymethyl groups (-CH COOH): eliminated by such
2
0,2-1,5 per anydroglucose unit procedures and measures,
the additive and premixtures
Loss on drying: ≤ 12 %
shall be used with personal
Total glycolate: ≤ 0,4 % (as sodium skin, eye and breathing
glycolate on the anhydrous basis) protective equipment.
Sodium: ≤ 12,4 % (on the anhydrous
basis)
Analytical method(1)
For the identification/characterisation of
sodium carboxymethyl cellulose in the
feed additive:
— Regulation (EU) No 231/2012 for
sodium carboxymethyl cellulose
and the corresponding methods of
FAO JECFA ‘sodium carboxymethyl
cellulose’ monograph and the
‘Volume 4’ of FAO JECFA combined
compendium for food additives
specifications.
(1) Details of the analytical methods are available at the following address of the Reference Laboratory: https://joint-research-centre.ec.europa.eu/eurl-fa-eurl-feed-additives/eurl-fa-authorisation/eurl-fa-
evaluation-reports_en.
ELI:
http://data.europa.eu/eli/reg_impl/2025/157/oj
41/41
OJ
L,
30.1.2025
EN