See Full Document Text
Official Journal EN
of the European Union L series
2025/1800 19.9.2025
COMMISSION IMPLEMENTING REGULATION(EU) 2025/1800
of 10 September 2025
amending Implementing Regulation (EU) 2023/753 as regards administrative changes to the Union
authorisation for the biocidal product family ‘C(M)IT/MIT formulations’
(Text with EEA relevance)
THE EUROPEAN COMMISSION,
Having regard to the Treaty on the Functioning of the European Union,
Having regard to Regulation (EU) No 528/2012 of the European Parliament and of the Council of 22 May 2012 concerning
the making available on the market and use of biocidal products(1), and in particular Article 50(2) thereof,
Whereas:
(1) On 12 April 2023, Commission Implementing Regulation (EU) 2023/753(2)granted a Union authorisation, under
number EU-0025678-0000, to Solenis Switzerland GmbH for the making available on the market and use of the
biocidal product family ‘C(M)IT/MIT formulations’. The Annex to that Implementing Regulation provides the
summary of product characteristics for that biocidal product family.
(2) On 1 October 2024, Solenis Switzerland GmbH submitted to the European Chemicals Agency (‘the Agency’), in
accordance with Article 11(1) of Commission Implementing Regulation (EU) No 354/2013(3), a notification of
administrative change to the Union authorisation for the biocidal product family ‘C(M)IT/MIT formulations’,
recorded in the register for biocidal products under case number BC-TG100256-47. The notified proposed change
concerns the addition of formulators of the biocidal product.
(3) On 6 November 2024(4), the Agency submitted to the Commission, in accordance with Article 11(3) of
Implementing Regulation (EU) No 354/2013, an opinion on the notified administrative change to the Union
authorisation for the biocidal product family ‘C(M)IT/MIT formulations’. In the opinion, the Agency concludes that
the proposed change is an administrative change as referred to in Article 50(3), point (a), of Regulation (EU)
No 528/2012 and as specified in Title 1, Section 2, of the Annex to Implementing Regulation (EU) No 354/2013,
and that after the implementation of the change, the conditions of Article 19 of Regulation (EU) No 528/2012 will
still be met.
(4) On 6 November 2024, the Agency transmitted to the Commission the revised summary of the biocidal product
characteristics of the Union authorisation for the biocidal product family ‘C(M)IT/MIT formulations’ in all official
languages of the Union, covering the administrative change applied for, in accordance with Article 11(6) of
Implementing Regulation (EU) No 354/2013.
(5) The Commission concurs with the opinion of the Agency and therefore considers it appropriate to amend the Union
authorisation for the biocidal product family ‘C(M)IT/MIT formulations’ to introduce the administrative change
requested by Solenis Switzerland GmbH.
(1) OJ L 167, 27.6.2012, p. 1, ELI: http://data.europa.eu/eli/reg/2012/528/oj.
(2) Commission Implementing Regulation (EU) 2023/753 of 12 April 2023 granting a Union authorisation for the biocidal product
family “C(M)IT/MIT formulations” (OJ L 100, 13.4.2023, p. 48, ELI: http://data.europa.eu/eli/reg_impl/2023/753/oj).
(3) Commission Implementing Regulation (EU) No 354/2013 of 18 April 2013 on changes of biocidal products authorised in accordance
with Regulation (EU) No 528/2012 of the European Parliament and of the Council (OJ L 109, 19.4.2013, p. 4, ELI: http://data.europa.
eu/eli/reg_impl/2013/354/oj).
(4) ECHA opinion UAD-C-1777770-16-00/F of 6 November 2024 on administrative changes of the Union authorisation of the biocidal
product family ‘C(M)IT/MIT formulations’, https://echa.europa.eu/opinions-on-union-authorisation.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 1/38EN
OJ L, 19.9.2025
(6) Except for the amendments regarding the administrative change, all other information included in the summary of
the biocidal product characteristics of ‘C(M)IT/MIT formulations’ as set out in Annex to Implementing Regulation
(EU) 2023/753 remain unchanged.
(7) In order to enhance clarity and to ease the access of users and interested parties to the consolidated version of the
summary of the biocidal product characteristics which is to be published by the Agency, the Annex to Implementing
Regulation (EU) 2023/753 should be replaced in its entirety. Due to a change in the format used for the generation of
the summary of biocidal product characteristics in the register for biocidal products in February 2024, the summary
of biocidal product characteristics in that Annex should also include some minor editorial and layout changes.
(8) Implementing Regulation (EU) 2023/753 should therefore be amended accordingly,
HAS ADOPTED THIS REGULATION:
Article 1
The Annex to Implementing Regulation (EU) 2023/753 is replaced by the text set out in the Annex to this Regulation.
Article 2
This Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the
European Union.
This Regulation shall be binding in its entirety and directly applicable in all Member States.
Done at Brussels, 10 September 2025.
For the Commission
The President
Ursula VON DER LEYEN
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ANNEX
SUMMARY OF PRODUCT CHARACTERISTICS FOR A BIOCIDAL PRODUCT FAMILY
C(M)IT/MIT formulations
Product type(s)
PT06: Preservatives for products during storage
PT11: Preservatives for liquid-cooling and processing systems
PT12: Slimicides
Authorisation number:EU-0025678-0000
R4BP asset number:EU-0025678-0000
PART I.
FIRST INFORMATION LEVEL
1. ADMINISTRATIVE INFORMATION
1.1. Family name
Name C(M)IT/MIT formulations
1.2. Product type(s)
Product type(s) PT06: Preservatives for products during storage
PT11: Preservatives for liquid-cooling and processing
systems
PT12: Slimicides
1.3. Authorisation holder
Name Solenis Switzerland GmbH
Name and address of the authorisation holder
Address Mühlentalstrasse 38 8200 Schaffhausen CH
Authorisation number EU-0025678-0000
R4BP asset number EU-0025678-0000
Date of the authorisation 3 May 2023
Expiry date of the authorisation 31 August 2032
1.4. Manufacturer(s) of the product
Name of manufacturer Solenis Switzerland GmbH
Address of manufacturer Mühlentalstrasse 38 8200 Schaffhausen Switzerland
Location of manufacturing sites Solenis Switzerland GmbH site 1
Fütingsweg 20 D-47805 Krefeld Germany
Solenis Switzerland GmbH site 2
Wimsey Way, Somercotes DE55 4PA Alfreton United
Kingdom of Great Britain and Northern Ireland (the)
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Name of manufacturer Solenis Switzerland GmbH
Solenis Switzerland GmbH site 3
Högastensgatan 18 252 32 Helsingborg Sweden
Solenis Switzerland GmbH site 4
AD International B.V. Markweg Zuid 27 4793 ZJ
Fijnaart Netherlands (the)
Name of manufacturer Diversey UK Production Ltd
Address of manufacturer Cotes Park Industrial Estate, Somercotes DE55 4PA
Alfreton United Kingdom of Great Britain and
Northern Ireland (the)
Location of manufacturing sites Diversey UK Production Ltd
Cotes Park Industrial Estate, Somercotes, DE55 4PA
Alfreton United Kingdom of Great Britain and
Northern Ireland (the)
Name of manufacturer Diversey Italy Production Srl
Address of manufacturer Strada Statale 235 26010 Bagnolo Cremasco (CR) Italy
Location of manufacturing sites Diversey Italy Production Srl
Strada Statale 235 26010 Bagnolo Cremasco (CR) Italy
Name of manufacturer Diversey España Production S.L.U
Address of manufacturer Avenida Conde Duque 5, 7 y 9, Poligono Industrial La
Postura 28343 Valdemoro (Madrid) Spain
Location of manufacturing sites Diversey España Production S.L.U
Avenida Conde Duque 5, 7 y 9, Poligono Industrial La
Postura 28343 Valdemoro (Madrid) Spain
Name of manufacturer Diversey Netherlands Production BV
Address of manufacturer Rembrandtlaan 414 7545ZW Enschede Netherlands
(the)
Location of manufacturing sites Diversey Netherlands Production BV
Rembrandtlaan 414 7545ZW Enschede Netherlands
(the)
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Name of manufacturer Diversey Germany Production oHG
Address of manufacturer Morschheimer Strasse 12 67292 Kirchheimbolanden
Germany
Location of manufacturing sites Diversey Germany Production oHG
Morschheimer Strasse 12 67292 Kirchheimbolanden
Germany
1.5. Manufacturer(s) of the active substance(s)
Active substance C(M)IT/MIT (3:1)
Name of manufacturer Specialty Electronic Materials Switzerland GmbH
Address of manufacturer Bachtobelstrasse 3 8810 Horgen Switzerland
Location of manufacturing sites Specialty Electronic Materials Switzerland GmbH site 1
Jiangsu FOPIA Chemicals Co., Ltd, Touzeng Village
224555 Binhuai Town, Binhai County, Yancheng City,
Jiangsu, China
Specialty Electronic Materials Switzerland GmbH site 2
Rohm and Haas (UK) Ltd. Tyneside Works, Ellison
Street, NE32 3DJ Jarrow United Kingdom of Great
Britain and Northern Ireland (the)
Active substance C(M)IT/MIT (3:1)
Name of manufacturer Thor GmbH
Address of manufacturer Landwehrstraße 1 67346 Speyer Germany
Location of manufacturing sites Thor GmbH site 1
Landwehrstraße 1 67346 Speyer Germany
Active substance C(M)IT/MIT (3:1)
Name of manufacturer Thor Quimicos de México, SA de CV
Address of manufacturer Km 182 Autopista México – Querétaro, Pedro
Escobedo 76700 Querétaro Mexico
Location of manufacturing sites Thor Quimicos de México, SA de CV site 1
Km 182 Autopista México – Querétaro, Pedro
Escobedo 76700 Querétaro Mexico
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Active substance C(M)IT/MIT (3:1)
Name of manufacturer Troy Chemical Company BV
Address of manufacturer Poortweg 4C 2612 Delft Netherlands (the)
Location of manufacturing sites Troy Chemical Company BV site 1
Weifang Heaven-sent New Materials Technology Co.
Ltd, Binhai Road, Changyi Coastal Economic
Development Zone 261312 Weifang China
Troy Chemical Company BV site 2
Dalian Xingyuan Chemistry Co., Ltd, Room
1205/1206, Pearl River International Building, No.99,
Xinkai Road, Xigang District, Songmudao Chemical
Industry Zone, Puwan New District 116308 Dalian
China
Troy Chemical Company BV site 3
Dalian Bio-Chem Company Limited, Songmudao Plant:
Songmudao Chemical Industry, Zone, Puwan New
District 116308 Dalian China
Active substance C(M)IT/MIT (3:1)
Name of manufacturer Jiangsu FOPIA Chemicals Co., Ltd
Address of manufacturer Touzeng Village, Binhuai Town, Binhai County
224555 Yancheng City China
Location of manufacturing sites Jiangsu FOPIA Chemicals Co., Ltd site 1
Touzeng Village, Binhuai Town, Binhai County
224555 Yancheng City China
2. PRODUCT FAMILY COMPOSITION AND FORMULATION
2.1. Qualitative and quantitative information on the composition of the family
Common name IUPAC name Function CAS number EC number Content (%)
C(M)IT/MIT (3:1) Reaction mass of active 55965-84-9 2,2 - 20,9 % (w/w)
5-chloro- substance
2-methyl-2h-
isothiazol-3-one
and 2-methyl-2h-
isothiazol-3-one
(3:1)
2.2. Type(s) of formulation
Formulation type(s) AL Any other liquid
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PART II.
SECOND INFORMATION LEVEL - META SPC(S)
1. META SPC 1 ADMINISTRATIVE INFORMATION
1.1. Meta SPC 1 identifier
Identifier Meta SPC: Meta SPC 3
1.2. Suffix to the authorisation number
Number 1-1
1.3. Product type(s)
Product type(s) PT06: Preservatives for products during storage
PT11: Preservatives for liquid-cooling and processing
systems
PT12: Slimicides
2. META SPC 1 COMPOSITION
2.1. Qualitative and quantitative information on the composition of the meta SPC 1
Common name IUPAC name Function CAS number EC number Content (%)
C(M)IT/MIT (3:1) Reaction mass of active 55965-84-9 2,2 - 6,5 % (w/w)
5-chloro- substance
2-methyl-2h-
isothiazol-3-one
and 2-methyl-2h-
isothiazol-3-one
(3:1)
2.2. Type(s) of formulation of the meta SPC 1
Formulation type(s) AL Any other liquid
3. HAZARD AND PRECAUTIONARY STATEMENTS OF THE META SPC 1
Hazard statements H332: Harmful if inhaled.
H314: Causes severe skin burns and eye damage.
H317: May cause an allergic skin reaction.
H410: Very toxic to aquatic life with long lasting
effects.
H290: May be corrosive to metals.
H302: Harmful if swallowed.
EUH071: Corrosive to the respiratory tract.
Precautionary statements P260: Do not breathe fume.
P264: Wash skin thoroughly after handling.
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P270: Do not eat, drink or smoke when using this
product.
P272: Contaminated work clothing should not be
allowed out of the workplace.
P273: Avoid release to the environment.
P280: Wear protective gloves/ protective clothing/ eye
protection/ face protection/ hearing protection.
P362+P364: Take off contaminated clothing and wash
it before reuse.
P333+P313: If skin irritation or rash occurs: Get
medical advice.
P301+P330+P331: IF SWALLOWED: rinse mouth. Do
NOT induce vomiting.
P303+P361+P353: IF ON SKIN (or hair): Take off
immediately all contaminated clothing. Rinse skin with
water [or shower].
P304+P340: IF INHALED: Remove person to fresh air
and keep comfortable for breathing.
P310: Immediately call a POISON CENTER/ doctor.
P305+P351+P338: IF IN EYES: Rinse cautiously with
water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
P391: Collect spillage.
P405: Store locked up.
P234: Keep only in original packaging.
P301+P312: IF SWALLOWED: Call a POISON
CENTER/ doctor if you feel unwell.
P406: Store in a a corrosion-resistant container with a
resistant inner liner.
P390: Absorb spillage to prevent material damage.
4. AUTHORISED USE(S) OF THE META SPC
4.1. Use description
Table 1
Preservation of polymer lattices
Product type PT06: Preservatives for products during storage
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
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Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Field(s) of use Indoor use
Preservation of polymer latexes
The biocidal product is recommended for the control of bacteria,
yeast and fungi in the manufacture, storage, and transport of
latexes, synthetic polymers including Hydrolysed Poly Acryl
Amide (HPAM) and biopolymers (e.g. xanthan, dextran..) natural
latexes.
Application method(s) Method: closed system
Detailed description:
Manual and automated application. The biocidal product should
be dispensed to the end use fluid at a point to ensure adequate
mixing using preferably automated metering pump or by manual
addition.
Application rate(s) and frequency Application rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the
biocidal products; Professional uses: 14,9 - 50 mg /kg of C(M)
IT/MIT (3:1) in final product. -
Number and timing of application:
The biocidal product is added at single dose at the time of
manufacture, storage or shipment.
To ensure uniform distribution, slowly disperse using automated
metering or manual addition, into product with agitation. Mix
thoroughly until evenly dispersed throughout the product.
Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products.
Professional uses
14,9 - 50 mg /kg of C(M)IT/MIT (3:1) in final product.
For the biocidal product as supplied: for industrial use only.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.1.1. Use-specific instructions
— The preservative can be added at any stage of the production of the product.
— Earliest possible addition is recommended for optimal protection.
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— Consult the manufacturer to determine the optimal dosage for the various products to be preserved.
— It is recommended that the optimum biocide concentration and compatibility with individual formulations
is determined by means of laboratory tests.
— The duration and storage conditions of the preserved matrices may impact the efficacy of the product,
microbiological tests should be conducted to determine the appropriate application rate without exceeding
the maximum authorised application rate.
— The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to
professional users.
4.1.2. Use-specific risk mitigation measures
— During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the
product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
— The maximal products concentration used for the preservation of polymer lattices being above the threshold
value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes
potentially exposed, and application of technical and organisational RMM:
— Minimisation of manual phases;
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Good standard of general ventilation;
— Training and management of staff on good practice.
4.1.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.1.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
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4.1.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.2. Use description
Table 2
Preservation of mineral slurries
Product type PT06: Preservatives for products during storage
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Field(s) of use Indoor use
Preservation of mineral slurries
The biocidal product is recommended to control the growth of
bacteria in aqueous-based inorganic/mineral slurries and inorganic
pigments which are formulated into paints, coatings and paper.
Application method(s) Method: closed system
Detailed description:
Manual and automated application. The biocidal product should
be dispensed as a tankside additive into the circulating use-dilution
of the fluid, using a metering pump or by manual pouring, at a
point to assure adequate mixing throughout the system.
Application rate(s) and frequency Application rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the
biocidal products; Professional uses: 10- 30 mg/kg of C(M)IT/MIT
(3:1) in final product. -
Number and timing of application:
The biocidal product is added at single dose at the time of
manufacture, storage or shipment.
Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products.
Professional uses:
10- 30 mg/kg of C(M)IT/MIT (3:1) in final product.
For the biocidal product as supplied: for industrial use only.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
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4.2.1. Use-specific instructions
— The preservative can be added at any stage of the production of the product.
— Earliest possible addition is recommended for optimal protection.
— Consult the manufacturer to determine the optimal dosage for the various products to be preserved.
— It is recommended that the optimum biocide concentration and compatibility with individual formulations
is determined by means of laboratory tests.
— The duration and storage conditions of the preserved matrices may impact the efficacy of the product,
microbiological tests should be conducted to determine the appropriate application rate without exceeding
the maximum authorised application rate.
— The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to
professional users.
4.2.2. Use-specific risk mitigation measures
— During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the
product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
— The maximal products concentration used for the preservation of mineral slurries being above the threshold
value of 15 ppm, exposure has to be limited by use of PPE, protecting skin and mucous membranes
potentially exposed, and application of technical and organisational RMM:
— Minimisation of manual phases;
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Good standard of general ventilation;
— Training and management of staff on good practice.
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4.2.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.2.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.2.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.3. Use description
Table 3
Preservation of functional fluids (hydraulic fluids, antifreeze, corrosion inhibitors, etc. - excluding
fuel additives)
Product type PT06: Preservatives for products during storage
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Field(s) of use Indoor use
Preservation of functional fluids (hydraulic fluids, antifreeze,
corrosion inhibitors, etc. - excluding fuel additives)
The biocidal product is recommended to control the growth of
bacteria in functional fluids such as brake and hydraulic fluids,
antifreeze additives, corrosion inhibitors, spinning fluids. The
biocidal product inhibits the growth microorganisms, which
would otherwise lead to odours formation, viscosity alteration,
discolouration of product and premature product failure.
Application method(s) Method: closed system
Detailed description:
Manual and automated dosing. The biocidal product should be
dispensed to the end use fluid at a point to ensure adequate
mixing using preferably automated metering pump or by manual
addition.
Application rate(s) and frequency Application rate: Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the
biocidal products. Professional uses: Add at a typical use rate
between 6 to 30 mg C(M)IT/MIT (3:1) per kg final product to be
treated. -
Number and timing of application:
The biocidal product is added at single dose at time of
manufacturing, storage or shipment.
Industrial uses: 1,5 - 14,5 % C(M)IT/MIT in the biocidal products.
Professional uses:
Add at a typical use rate between 6 to 30 mg C(M)IT/MIT (3:1) per
kg final product to be treated
For the biocidal product as supplied: for industrial use only.
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Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.3.1. Use-specific instructions
— The preservative can be added at any stage of the production of the product.
— Earliest possible addition is recommended for optimal protection.
— Consult the manufacturer to determine the optimal dosage for the various products to be preserved.
— It is recommended that the optimum biocide concentration and compatibility with individual formulations
is determined by means of laboratory tests.
— The duration and storage conditions of the preserved matrices may impact the efficacy of the product,
microbiological tests should be conducted to determine the appropriate application rate without exceeding
the maximum authorised application rate.
— The biocidal product shall be used for treatment of products (articles/mixtures) distributed only to
professional users.
4.3.2. Use-specific risk mitigation measures
— During handling phases of products from Meta SPC 1, 2, 3 and 4 (mixing and loading), exposure to the
product (corrosive and skin sensitizer products) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
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— The maximal products concentration used for the preservation of functional fluids (hydraulic fluids,
antifreeze, corrosion inhibitors, etc…) being above the threshold value of 15 ppm, exposure has to be
limited by use of PPE, protecting skin and mucous membranes potentially exposed, and application of
technical and organisational RMM:
— Minimisation of manual phases;
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Good standard of general ventilation;
— Training and management of staff on good practice.
4.3.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.3.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.3.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.4. Use description
Table 4
Preservation of liquids used in closed recirculating cooling systems
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria (including Legionella pneumophila)
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Field(s) of use Indoor use
Outdoor use
Preservation of liquids used in closed recirculating cooling systems
(Closed re-circulating cooling water systems comprise compressor
cooling, air conditioning chilled water, boilers, engine jacket
cooling, power supply cooling, and other industrial processes).
The biocidal product is used to control the growth of aerobes and
anaerobes bacteria, yeast, fungi, and biofilm in the circulating
water of closed systems
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 15/38EN
OJ L, 19.9.2025
Application method(s) Method: closed system
Detailed description:
Manual and automated dosing.
Application rate(s) and frequency Application rate: Curative efficacy:- against bacteria (including L.
pneumophila) at 5 - 14,9 g C(M)IT/MIT (3:1) / m3of water.
Contact time: 24 hours - against biofilm: 14,9 g C(M)IT/MIT (3:1) /
m3of water. Contact time: 24 hours.- against fungi and yeasts at 1
– 3 g C(M)IT/MIT (3:1) / m3of water. Contact time: 48 hours.
Preventive efficacy:- against bacteria (including L. pneumophila) at
3 – 14,9 g C(M)IT/MIT (3:1) / m3of water. - against biofilm
(including L. pneumophila): 3 g C(M)IT/MIT (3:1) / m3of water. -
Number and timing of application:
Curative efficacy:
— against bacteria (including L. pneumophila) at 5 - 14,9 g C(M)
IT/MIT (3:1) / m3of water.
Contact time: 24 hours
— against biofilm: 14,9 g C(M)IT/MIT (3:1) / m3of water.
Contact time: 24 hours
— against fungi and yeasts at 1 – 3 g C(M)IT/MIT (3:1) / m3of
water.
Contact time: 48 hours
Preventive efficacy:
against bacteria (including L. pneumophila) at 3 – 14,9 g C(M)
IT/MIT (3:1) / m3of water.
against biofilm (including L. pneumophila): 3 g C(M)IT/MIT (3:1) /
m3of water.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.4.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.4.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
16/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within the
product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product shall be
worn (coverall material to be specified by the authorisation holder within the product information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
4.4.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.4.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.4.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.5. Use description
Table 5
Preservation of liquids used in small open recirculating cooling systems
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria (including Legionella pneumophila)
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Scientific name: no data
Common name: Algae (green algae and cyanobacteria)
Development stage: no data
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 17/38EN
OJ L, 19.9.2025
Field(s) of use Indoor use
Outdoor use
Preservation of liquids used in small open recirculating cooling
systems (blowdown and recirculating flow rates, as well as total
volume of water limited to 2 m3/h, and 100 m3/h and 300 m3
respectively)
Process and cooling water: Used to control the growth of bacteria,
algae, fungi and biofilm
Application method(s) Method: open system
Detailed description:
Manual and automated dosing.
Application rate(s) and frequency Application rate: Curative treatment Against bacteria (including L.
pneumophila) at 5 – 14,9 g C(M)IT/MIT (3:1) / m3of water , -
against biofilm (including L. pneumophila) at 1,5 to 14,9 g C(M)
IT/MIT (3:1) / m3of water, - against fungi (including yeast) at 1 –
14,9 g C(M)IT/MIT (3:1) / m3of water. Preventive treatment: -
Against bacteria, green algae and cyanobacteria at 3 g C(M)IT/MIT
(3:1) / m3of water, - against biofilm (including L. pneumophila) at
3 g C(M)IT/MIT (3:1) / m3of water. -
Number and timing of application:
Curative treatment:
— Against bacteria (including L. pneumophila) at 5 – 14,9 g C(M)
IT/MIT (3:1) / m3of water
Contact time: 24 hours
— against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)
IT/MIT (3:1) / m3of water
Contact time: 48 hours.
— against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3of
water
Contact time: 48 hours.
Preventive treatment:
— against bacteria, green algae and cyanobacteria at 3 g C(M)
IT/MIT (3:1) / m3of water.
— against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT
(3:1) / m3of water.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
18/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
4.5.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.5.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
— Cooling fluid must not enter surface water directly. Use product only in premises that are connected to
a STP.
— The product can only be used when the cooling towers are equipped with drift eliminators that reduce the
drift at least by 99%.
4.5.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.5.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.5.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 19/38EN
OJ L, 19.9.2025
4.6. Use description
Table 6
Preservation of liquids used in pasteurizers, conveyor belts and air washers
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria (including Legionella pneumophila)
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Scientific name: no data
Common name: Algae (green algae and cyanobacteria)
Development stage: no data
Field(s) of use Indoor use
Outdoor use
Preservation of liquids used in non-food pasteurizers and
conveyor belts, air washers.
Application method(s) Method: -
Detailed description:
The biocidal product is dosed automatically in the heat transfer
fluid, in a place of good mixing (e.g. collecting sump below the
conveyor belt). The feeding pipe is used to dose the biocidal
product below the water level in order to limit its evaporation.
Application rate(s) and frequency Application rate: Curative treatment: -against bacteria (including L.
pneumophila): 5 - 14,9 g C(M)IT/MIT (3:1) / m3of water - against
biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)IT/MIT
(3:1) / m3of water - against fungi and yeast at 1 – 14,9 g C(M)
IT/MIT (3:1) / m3of water. Preventive treatment: Against bacteria,
green algae and cyanobacteria at 3 g C(M)IT/MIT (3:1) / m3 of
water, against biofilm (including L. pneumophila) at 3 g C(M)
IT/MIT (3:1) / m3of water. -
Number and timing of application:
Curative treatment:
against bacteria (including L. pneumophila): 5 - 14,9 g C(M)IT/MIT
(3:1) / m3of water.
Contact time: 24 hours
— against biofilm (including L. pneumophila) at 1,5 - 14,9 g C(M)
IT/MIT (3:1) / m3of water
Contact time: 48 hours.
— against fungi and yeast at 1 – 14,9 g C(M)IT/MIT (3:1) / m3of
water
Contact time: 48 hours.
20/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
Preventive treatment:
— Against bacteria, green algae and cyanobacteria at 3 g C(M)
IT/MIT (3:1) / m3of water.
— against biofilm (including L. pneumophila) at 3 g C(M)IT/MIT
(3:1) / m3of water.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.6.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
Air washers: For use only in industrial air-washer systems that maintain effective mist eliminating components.
4.6.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 21/38EN
OJ L, 19.9.2025
4.6.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.6.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.6.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.7. Use description
Table 7
Preservation of recirculating fluids used in textile and fiber processing, leather processing, photo-
processing and fountain solution systems
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Field(s) of use Indoor use
Preservation of recirculating fluids used in textile, fiber processing,
leather processing, photo-processing and fountain solution
systems
C(M)IT/MIT (3:1) biocidal products are used for the preservation
of textile and spinning fluids, photo processing solutions, leather
process (e.g. washing and soaking treatment stages) and printing
fountain solutions to control the integrity of recirculating fluid by
reducing microbial contamination in the bulk solution.
Application method(s) Method: -
Detailed description:
Manual and automated dosing. The preservation of all end-
products is performed in most cases highly automated by
industrial users. The biocidal product is added to the central sump,
basin or recirculating lines in an area with adequate mixing.
Application rate(s) and frequency Application rate: Curative treatment: Against bacteria at 16-30 mg
C(M)IT/MIT (3:1) per L of fluid -
Number and timing of application:
Curative treatment: Against bacteria at 16-30 mg C(M)IT/MIT
(3:1) per L of fluid
Contact time 5 days
Category(ies) of users Industrial
22/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.7.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.7.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
— Liquids used in textile and fiber processing fluids must not enter surface water directly. Use product only in
premises that are connected to a STP.
— Recirculating liquids in photoprocessing systems and fountain solution systems must not enter surface water
directly. Use product only in premises that are connected to a STP.
4.7.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 23/38EN
OJ L, 19.9.2025
4.7.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.7.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.8. Use description
Table 8
Preservation of re-circulating liquids used in paint spray booths and electrodeposition coating systems
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Field(s) of use Indoor use
Preservation of re-circulating liquids used in paint spray booths
and electrodeposition coating systems.
The biocidal product is used for preservation of fluids in pre-
treatment processes (Cleaning treatment for grease removal and
soil, degreasing Phosphating process, Rinse off tanks) paint spray
booths and electrodeposition coating systems (e.g. cataphoretic
baths) applied in Car Refinishing and Original equipment Car
Manufacturing to control the integrity of recirculating fluid by
reducing microbial contamination from bacteria and fungi in the
bulk solution.
Application method(s) Method: -
Detailed description:
-
Application rate(s) and frequency Application rate: Preventive treatment: 7,5 to 30 mg C(M)IT/MIT
(3:1) per Kg final product. -
Number and timing of application:
Preventive treatment: 7,5 to 30 mg C(M)IT/MIT (3:1) per Kg final
product.
The biocidal product is added at the time of manufacture, storage
or shipment.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
24/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
4.8.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.8.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
4.8.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.8.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.8.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.9. Use description
Table 9
Preservation of liquids used in closed recirculating heating systems and associated pipework
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 25/38EN
OJ L, 19.9.2025
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria (anaerobes and aerobes (including
Legionella pneumophila)
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Field(s) of use Indoor use
Outdoor use
Preservation of liquids used in closed recirculating heating systems
and associated pipework. Pre-commission biocide flushing of new
or existing pipework systems (heating and chilling pipework)
includes used or new structural pipework built on industrial
building projects.
Closed recirculating heating systems: pre-commission biocidal
product flushing of new or existing pipework systems (heating
and chilling pipework) includes used or new structural pipework
built on industrial building projects. The biocidal product is used
to control the growth of aerobic and anaerobic bacteria, fungi and
biofilm in the circulating water of closed systems. Closed systems
are less susceptible to corrosion, scaling and biological fouling
than open systems. However microbial problems can occur, if the
system is left filled and untreated. This is due to the presence of
nitrite and glycols used as nutrients by microbes.
Application method(s) Method: closed system
Detailed description:
Manual and automated dosing. The biocidal product is dosed
automatically in the heat transfer fluid, in a place of good mixing.
The feeding pipe must dose the biocidal product below the water
level in order to limit the evaporation of the biocidal product.
Application rate(s) and frequency Application rate: Curative treatment - against bacteria at 5 g C(M)
IT/MIT (3:1) / m3of water (including L. pneumophila) - against
biofilm at 14,9 g C(M)IT/MIT (3:1) / m3of water - against fungi
and yeast at 1 g C(M)IT/MIT / m3of water Preventive treatment -
against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT
(3:1) / m3of water - against biofilm at 3 g C(M)IT/MIT (3:1) / m3of
water. -
Number and timing of application:
Curative treatment:
— against bacteria at 5 g C(M)IT/MIT (3:1) / m3of water (including
L. pneumophila)
Contact time: 24 hours
— against biofilm at 14,9 g C(M)IT/MIT (3:1) / m3of water
Contact time: 24 hours
— against fungi and yeast at 1 g C(M)IT/MIT / m3of water Contact
time: 48 hours
Preventive treatment
— against bacteria (including L. pneumophila) at 3 g C(M)IT/MIT
(3:1) / m3of water and against biofilm at 3 g C(M)IT/MIT (3:1) /
m3of water.
26/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.9.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.9.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
4.9.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.9.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 27/38EN
OJ L, 19.9.2025
4.9.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.10. Use description
Table 10
Preservation of polymers used in oilfield processes (e.g. enhanced oil recovery, drilling muds, etc.)
Product type PT11: Preservatives for liquid-cooling and processing systems
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Field(s) of use Outdoor use
Preservation of polymers used in oilfield processes (e.g. enhanced
oil recovery, drilling muds, etc.)
Application method(s) Method: -
Detailed description:
-
Application rate(s) and frequency Application rate: Preventive treatment of polymers used in the
injection water: Xanthan polymer: 30 -50 g C(M)IT/MIT/m3
solution. HPAM polymer: 30 - 50 g C(M)IT/MIT/m3solution.
Preventive treatment of polymers used in the drilling muds:
Xanthan polymer: 30 g C(M)IT/MIT/m3solution. HPAM polymer:
30 g C(M)IT/MIT/m3solution. -
Number and timing of application:
Preventive treatment of polymers used in the injection water:
Xanthan polymer: 30 -50 g C(M)IT/MIT/m3solution.
HPAM polymer: 30 - 50 g C(M)IT/MIT/m3solution.
Preventive treatment of polymers used in the drilling muds:
Xanthan polymer: 30 g C(M)IT/MIT/m3solution.
HPAM polymer: 30 g C(M)IT/MIT/m3solution.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
28/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
4.10.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.10.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
4.10.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.10.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.10.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 29/38EN
OJ L, 19.9.2025
4.11. Use description
Table 11
Slimicide treatment in the de-inking process of the pulp and paper
Product type PT12: Slimicides
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Field(s) of use Indoor use
Slimicide treatment in the de-inking process of the pulp and
paper. Recycling paper /deinking paper mills. Deinking process is
a manufacturing paper process of removing printing inks from
waste paper-fibers to produce deinked pulp.
Application method(s) Method: closed system
Detailed description:
Manual and automated dosing. The biocidal product is
automatically dosed by pump and fixed pipes into the circuit,
usually in the pulper below the water level.
Application rate(s) and frequency Application rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT
(3:1) / m3of water to be treated. Preventive treatment: 5 g C(M)
IT/MIT (3:1) / m3of water to be treated. -
Number and timing of application:
Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3of water to
be treated
Contact time: 24 hours
Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3of water to be
treated.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
30/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
4.11.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.11.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
4.11.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.11.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.11.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.12. Use description
Table 12
Slimicide treatment in the wet-end stage of paper manufacturing process
Product type PT12: Slimicides
Where relevant, an exact description of the -
authorised use
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 31/38EN
OJ L, 19.9.2025
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
Scientific name: no data
Common name: Yeasts
Development stage: no data
Scientific name: no data
Common name: fungi
Development stage: no data
Field(s) of use Indoor use
Slimicide treatment in the wet-end stage of the paper
manufacturing process (paper mills, wet-end stage (water circuits),
and paper mills process system).
Application method(s) Method: closed system
Detailed description:
Manual and automated dosing.
Application rate(s) and frequency Application rate: Curative treatment: 10 to 14,9 g C(M)IT/MIT
(3:1) / m3of water to be treated. Preventive treatment: 5 g C(M)
IT/MIT (3:1) / m3of water to be treated. -
Number and timing of application:
Curative treatment: 10 to 14,9 g C(M)IT/MIT (3:1) / m3of water to
be treated
Contact time: 24 hours
Preventive treatment: 5 g C(M)IT/MIT (3:1) / m3of water to be
treated.
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.12.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.12.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
32/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
— The use of C(M)IT/MIT (3:1) containing products for the slimicide treatment in the wet-end stage of the
paper manufacturing process is restricted to
a) curative treatments in plants connected to a slimicide-free water from a pulp mill and only for the
treatment of the short circulation of the paper mill; and
b) preventive treatments,
and, for both cases, only if the factory’s waste water is purified in an on-site (full) industrial sewage treatment
plant with a minimal capacity of 5000 m3 per day as described in the Industrial Emission
Directive 2010/75/EU (Best Available Techniques for the production of pulp, paper and board) and if a
dilution of at least 200 times in surface water is achieved after the industrial sewage treatment plant.
4.12.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.12.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.12.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
4.13. Use description
Table 13
Preventive treatment (biofouling control) online and after cleaning in place for industrial RO/NF
membranes
Product type PT12: Slimicides
Where relevant, an exact description of the -
authorised use
Target organism(s) (including development Scientific name: no data
stage) Common name: Bacteria
Development stage: no data
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 33/38EN
OJ L, 19.9.2025
Field(s) of use Indoor use
Preventive treatment (biofouling control) online and after cleaning
in place for industrial RO/NF membranes
Application method(s) Method: closed system
Detailed description:
Manual and automated dosing.Biocidal product application on a
routine basis will prevent biofilm growth on Reverse Osmosis or
Nano Filtration membrane surfaces, feed spacer, filter media and
pipework. The biocidal product should be dispensed to the feed
water at a point to assure adequate mixing throughout the system.
Application rate(s) and frequency Application rate: Preventive treatment: 5 g C(M)IT/MIT (3:1) per
m3of fluid -
Number and timing of application:
Preventive treatment: 5 g C(M)IT/MIT (3:1) per m3of fluid
Category(ies) of users Industrial
Pack sizes and packaging material For industrial and professional users:
— HDPE flask: 5 L (nominal)
— HDPE Pail / Jerrycan: 10 L, 20 L, 25 L, 30 L (nominal)
— Box with HDPE liner: 20 L
— HDPE Drum: 110 L, 120 L, 200 L, 260 L
— HDPE IBC: 650 L, 800 L, 1 000 L, 1 250 L
All products should be transport and stored in a vented room.
4.13.1. Use-specific instructions
Microbiological tests to prove adequacy of preservation have to be undertaken by the user of C(M)IT/MIT products
in order to determine the effective dose of the preservative for the specific matrix/location/system. If needed,
consult the manufacturer of the preservative product.
4.13.2. Use-specific risk mitigation measures
— Rinse the system (especially the dispensing pumps) with water prior to perform the cleaning step.
— During handling phases (mixing and loading) and cleaning of the dispensing pumps, exposure to the
product (corrosive and skin sensitizer product) has to be limited by use of PPE and application of technical
and organisational RMM:
— Minimisation of manual phases (process automation);
— Use of a dosing device;
— Regular cleaning of equipment and work area;
— Avoidance of contact with contaminated tools and objects;
— Good standard of general ventilation;
— Training and management of staff on good practice.
34/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
— PPE is as follows:
— protective chemical resistant gloves (glove material to be specified by the authorisation holder within
the product information);
— protective coverall (at least type 3 or 4, EN 14605) which is impermeable for the biocidal product
shall be worn (coverall material to be specified by the authorisation holder within the product
information);
— Eye protection;
— Substance/task appropriate respirator if ventilation is inadequate.
— Use product only in premises that are connected to a STP.
4.13.3. Where specific to the use, the particulars of likely direct or indirect effects, first aid instructions and emergency measures to
protect the environment
See general directions for use.
4.13.4. Where specific to the use, the instructions for safe disposal of the product and its packaging
See general directions for use.
4.13.5. Where specific to the use, the conditions of storage and shelf-life of the product under normal conditions of storage
See general directions for use.
5. GENERAL DIRECTIONS FOR USE OF THE META SPC 1
5.1. Instructions for use
— The duration of the effect is dependent on the performance requirements of the customer for their preserved
material and on the specific ingredients composition and pH of the preserved product.
— Always read the label or leaflet before use and follow all the instructions provided.
— Respect the conditions of use of the product (concentration, contact time, temperature, pH, etc.)
PRECAUTIONARY MEASURES DURING STORAGE AND TRANSPORT:
Keep in a well-ventilated place. The product as supplied may evolve gas (largely carbon dioxide) slowly. To prevent
the buildup of pressure the product is packaged in specially vented containers, where necessary. Keep this product
in the original container when not in use. Container must be stored and transported in an upright position to
prevent spilling the contents through the vent, where fitted.
5.2. Risk mitigation measures
-
5.3. Particulars of likely direct or indirect effects, first aid instructions and emergency measures to protect
the environment
— Skin contact: Remove contaminated clothing and shoes. Wash contaminated skin with water. Contact
poison treatment specialist if symptoms occur.
— Eye contact: Immediately flush with plenty of water, occasionally lifting the upper and lower eyelids. Check
for and remove any contact lenses if easy to do. Continue to rinse with tepid water for at least 30 minutes.
Call 112/ambulance for medical assistance.
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 35/38EN
OJ L, 19.9.2025
— Ingestion: Wash out mouth with water. Contact poison treatment specialist. Seek medical advice
immediately if symptoms occur and/or large quantities have been ingested. Do not give fluids or induce
vomiting.
— Inhalation (of spray mist): Remove victim to fresh air and keep at rest in a position comfortable for
breathing. Seek medical advice immediately if symptoms occur and/or large quantities have been inhaled.
— In case of impaired consciousness place in recovery position and seek medical advice immediately.
— Keep the container or label available.
5.4. Instructions for safe disposal of the product and its packaging
— Do not discharge unused product on the ground, into water courses, into pipes (e.g. sink, toilets) nor down
the drains.
— Dispose of unused product, its packaging and all other waste, in accordance with local regulations.
5.5. Conditions of storage and shelf-life of the product under normal conditions of storage
Conditions for safe storage, including any incompatibilities: Keep in a dry, cool and well-ventilated place, in the
original container.
Shelf-life: 12 months
Protect from sunlight.
Recommendation: If a metal packaging is used, a varnish layer should be applied.
6. OTHER INFORMATION
-
7. THIRD INFORMATION LEVEL: INDIVIDUAL PRODUCTS IN THE META SPC 1
7.1. Trade name(s), authorisation number and specific composition of each individual product
Trade name(s) Spectrum™ Market area: EU
RX6804
MICROBIO
CIDE
Authorisation number EU-0025678-0001 1-1
Common name IUPAC name Function CAS number EC number Content (%)
C(M)IT/MIT Reaction mass active substance 55965-84-9 5,9 % (w/w)
(3:1) of 5-chloro-
2-methyl-2h-
isothiazol-
3-one
and 2-methyl-
2h-isothiazol-
3-one (3:1)
36/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/ojEN
OJ L, 19.9.2025
7.2. Trade name(s), authorisation number and specific composition of each individual product
Trade name(s) Spectrum™ Market area: EU
PR3126
PRESERVA
TIVE
Spectrum™ Market area: EU
RX8560
MICROBIO
CIDE
Spectrum™ Market area: EU
RX7827
MICROBIO
CIDE
Authorisation number EU-0025678-0002 1-1
Common name IUPAC name Function CAS number EC number Content (%)
C(M)IT/MIT Reaction mass active substance 55965-84-9 3,2 % (w/w)
(3:1) of 5-chloro-
2-methyl-2h-
isothiazol-
3-one
and 2-methyl-
2h-isothiazol-
3-one (3:1)
7.3. Trade name(s), authorisation number and specific composition of each individual product
Trade name(s) Biosperse™ Market area: EU
250
MICROBIO
CIDE
Biosperse™ Market area: EU
251
MICROBIO
CIDE
Biosperse™ Market area: EU
850
MICROBIO
CIDE
Biosperse™ Market area: EU
851
MICROBIO
CIDE
Spectrum™ Market area: EU
RX6810
MICROBIO
CIDE
Spectrum™ Market area: EU
RX6820
MICROBIO
CIDE
Authorisation number EU-0025678-0003 1-1
ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj 37/38EN
OJ L, 19.9.2025
Common name IUPAC name Function CAS number EC number Content (%)
C(M)IT/MIT Reaction mass active substance 55965-84-9 2,3 % (w/w)
(3:1) of 5-chloro-
2-methyl-2h-
isothiazol-
3-one
and 2-methyl-
2h-isothiazol-
3-one (3:1)
38/38 ELI: http://data.europa.eu/eli/reg_impl/2025/1800/oj