**Executive Summary**
A Letter of Intent (LoI) has been signed to establish the Centre of Excellence for CRISPR Innovation and Translation (CoE-CIT). This partnership between the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) and CRISPRBITS Private Limited aims to facilitate the translation of scientific discoveries using CRISPR technology into real-world clinical applications. The CoE-CIT will function as a public-private partnership to strengthen India's biotechnology and innovation ecosystem.
**Key Points / Main Content**
* **Purpose:**
* Establish the CoE-CIT to harness CRISPR technologies for translating scientific discoveries into clinical applications.
* **Partnership:**
* Joint effort between JNCASR and CRISPRBITS Private Limited.
* A public-private partnership between academia and industry.
* **Focus:**
* Developing affordable diagnostics using CRISPR gene-editing technology.
* Bridging the gap between biomedical research and therapeutic impact.
* **Vision:**
* To serve as a national model for academic-industry partnerships.
* Strengthen India's biotechnology and innovation ecosystem.
**Impact Analysis**
**JNCASR**
* **Impact:** The organization will be partnering with CRISPRBITS to plan the CoE on its campus and combine its strengths in fundamental biomedical sciences with CrisprBits' expertise in applied gene-editing and translational platforms.
* **Action Required:** Plan for CoE on its campus in partnership with CRISPRBITS.
**CRISPRBITS Private Limited**
* **Impact:** The organization will be partnering with JNCASR to plan the CoE.
* **Action Required:** Plan for CoE in partnership with JNCASR.
Key Entities Referenced
Centre of Excellence for CRISPR Innovation and Translation (CoE-CIT): A new center established to harness CRISPR technologies and translate scientific discoveries into clinical applications.
Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru: An autonomous institute of Department of Science and Technology (DST) that is partnering in establishing the CoE-CIT.
CRISPRBITS Private Limited: A Delhi-based biotechnology company focused on CRISPR gene-editing technology that is partnering in establishing the CoE-CIT.
Department of Science and Technology (DST): The department under which JNCASR functions.
Letter of Intent (LoI): The agreement signed to establish the Centre of Excellence for CRISPR Innovation and Translation (CoE-CIT).
Ministry of Science & Technology
LoI signed to establish Centre of Excellence for
CRISPR Innovation and Translation (CoE-CIT)
प्रव तथ: 22 DEC 2025 5:31PM by PIB Delhi
A new Letter of Intent (LoI) has been signed to establish a new Centre of Excellence for CRISPR
Innovation and Translation (CoE-CIT) as a dedicated hub to harness cutting-edge CRISPR technologies to
facilitate translation of scientific discoveries in a laboratory into real-world clinical applications.
The Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru an autonomous
institute of Department of Science and Technology (DST) and CRISPRBITS Private Limited (CrisprBits)
based in Delhi, focused on Biotechnology using CRISPR gene-editing technology for developing
affordable diagnostics, has announced the signing of a Letter of Intent (LOI) to jointly establish the CoE-
CIT, in a landmark public–private partnership between academia and industry which is among the first of
its kind in India.
The CoE-CIT is envisioned to bridge the bench to bed gap leading and have therapeutic impact by
combining JNCASR’s strengths in fundamental biomedical sciences with CrisprBits’ expertise in applied
gene-editing and translational platforms. Demonstrating how Indian scientific innovation can be
effectively translated into societal and clinical benefit, the CoE will serve as a replicable national model
for academic–industry partnerships to strengthen India’s biotechnology and innovation ecosystem.
“It is an exciting landmark event for JNCASR to plan this CoE on its campus partnering with
CRISPRBITS, known for building intelligent molecular platforms for development of scalable, affordable
innovative solutions in health sciences. Synergizing the mutual strengths in genetics, molecular and
chemical biology, and computational biology, this unique partnership will open a new route to impact
society and national missions,” says Umesh Waghmare, President of JNCASR.Fig 1: Prof. Umesh V Waghmare, President, JNCASR and Dr. Vijay Chandru, Co-Founder & CEO,
CRISPRBITS Pvt. Ltd. soon after the signing and exchange of the Expression of Interest document
Fig 2: Group photo of the members of the JNCASR and CRISPRBITS Pvt. Ltd. team, after signing the
Partnership document.
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NKR/AK
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