Read or download the official PDF of this gazette notification issued by the Ministry of Science and Technology on 6th August 2026. Classified under Press Release.
Executive Summary
The BioE3 Policy, implemented by the Department of Biotechnology (DBT), aims to establish biomanufacturing hubs and biofoundries to drive India's transition to a $300 billion bioeconomy by 2030. The policy focuses on six thematic verticals and five Bio-AI priority sectors, offering up to 70% financial assistance to eligible projects. It is expected to generate 1,500 direct and indirect jobs over the next five years, specifically targeting growth in Tier-II and Tier-III cities.
Key Points / Main Content
Thematic Verticals and Priority Sectors
Biomanufacturing Hubs: Six verticals identified: Bio-based chemicals/Bioplastics/APIs/Enzymes, Functional Foods/Smart Proteins, Precision Biotherapeutics, Climate-resilient agriculture, Biofuels/Carbon capture, and Marine/Space research.
Bio-AI Hubs: Five priority sectors established: Ayurveda, Agriculture Innovations, Genome Diagnostics, Synthetic Biology, and Biomolecular Design.
Project Selection and Evaluation Process
Submission: Proposals and Letters of Intent are invited through national calls and advertisements.
Screening: A 'Screening Committee' evaluates proposals based on defined eligibility and technical criteria.
Technical & Financial Review: A 'Selection Committee' reviews technical aspects, while a 'Financial Evaluation Committee' (FEC) assesses co-funding, equity financing, and royalty-sharing modalities.
Approval: The 'Apex Committee' provides final recommendations based on defined milestones, costs, and disbursement mechanisms.
Funding and Economic Impact
Financial Support: The policy provides up to 70% of project costs as financial assistance; the private sector is expected to contribute the remaining 30%.
Investment to Date: Private sector investment commitments have already reached Rs. 602.09 Cr.
Infrastructure: Over 600 beneficiaries have utilized established biofoundries and biomanufacturing hubs for scaling and validating bio-based technologies.
Impact Analysis
Start-ups, MSMEs, and Private IndustryImpact
They gain access to high-performance biomanufacturing infrastructure and financial assistance for scaling and validating innovations. This facilitates the "Make-in-India" initiative and bridges the gap between discovery-led research and development.
Action Required
Interested entities must respond to national calls for proposals and must be prepared to contribute 30% of the total project cost.
Workforce in Tier-II and Tier-III CitiesImpact
The policy is projected to create approximately 1,500 direct and indirect employment opportunities within these regions over the next five years.
Action Required
Local talent and job seekers should monitor opportunities arising from the development of regional biomanufacturing hubs and hubs for Bio-AI.
Biotechnology Research and Development SectorImpact
The sector benefits from a structured framework for indigenous biomanufacturing across diverse fields, including genomics, biotherapeutics, and climate-resilient agriculture.
Action Required
Researchers and institutions must align their projects with the six thematic verticals and five priority Bio-AI sectors to qualify for policy-led "Bioenabler" support.
Key Entities Referenced
BioE3 Policy: The 'Biotechnology for Economy, Environment and Employment' policy aimed at fostering innovation-led growth to achieve a $300 billion bioeconomy by 2030.
Department of Biotechnology (DBT): The primary department responsible for identifying thematic verticals and establishing bioenablers like Biomanufacturing Hubs and Biofoundries.
Biomanufacturing Hubs and Biofoundries: Key infrastructure established under the BioE3 policy to enable the scale-up and validation of bio-based technologies for start-ups, MSMEs, and private industry.
Bio-AI hubs: Specialized centers focused on five priority sectors including Ayurveda, Agriculture Innovations, Genome Diagnostics, Synthetic Biology, and Biomolecular Design.
Make-in-India: A national initiative supported by the BioE3 policy to strengthen indigenous manufacturing capabilities and attract private sector investment in the biotech sector.
Ministry of Science & Technology
PARLIAMENT QUESTION: Contribution of BioE3
Policy
प्रव तथ: 06 AUG 2026 2:56PM by PIB Delhi
The Department of Biotechnology (DBT) has identified six thematic verticals in the BioE3
(Biotechnology for Economy, Environment and Employment) policy for establishing Biomanufacturing
Hubs and Biofoundries. They are as follows:
i. Bio-based chemicals, Bioplastics, Active Pharmeceutical Ingredients (APIs), and Enzymes
ii. Functional Foods and Smart Proteins
iii. iii. Precision Biotherapeutics (monoclonal antibodies, mRNA therapeutics, cell & gene
therapy)
iv. iv. Climate resilient agriculture (agri-biologicals)
v. Biofuels and Carbon capture
vi. vi. Futuristic marine and space research
Five priority sectors are identified for establishment of Bio-AI hubs:
i. Ayurveda
ii. Agriculture Innovations
iii. Genome Diagnostics
iv. Synthetic Biology
v. Biomolecular Design
The Bioenablers which include Biomanufacturing Hubs, Biofoundries and Bio-AI hubs are established
after rigorous multi-tier evaluation of proposals received in response to the nationwide call for proposals
through advertisements. Following criteria have been adopted for selection:
i. Letter of Intent /Proposals invited through national calls.
ii. Screening of the proposals done through ‘Screening Committee’ based on the defined
eligibility criteria. The proposals are selected based on Technical evaluation followed by
Financial Evaluation.
iii. The ‘Selection Committee’ evaluated the technical aspects of the proposals taking into
consideration the experts comments and the presentation.
iv. The ‘Financial Evaluation Committee (FEC)’ evaluated the proposals w.r.t financial
mechanisms/modalities such as co-funding/equity financing & management/royalty sharing,
etc.
v. Selection of proposals with defined objectives/milestones, deliverables, duration, total cost,
funds disbursement mechanisms/modalities, etc. are recommended by the Apex Committee
The implementation of the BioE3 Policy is expected to generate approximately 1500 direct and indirect
employment opportunities over the next five years in Tier-II and Tier-III cities.To promote indigenous bio-manufacturing and encourage participation of start-ups, MSMEs, and private
industry, under BioE3 policy, financial assistance of up to 70% of the project cost is provided, while the
remaining 30% of the project cost is expected to be contributed by the private sector.
The BioE3 Policy is expected to significantly contribute towards achieving the target of a $300 billion
bioeconomy by 2030 by fostering innovation-led growth, strengthening indigenous bio-manufacturing
capabilities, and expanding the biotechnology ecosystem.
The policy aims to promote high-performance biomanufacturing by establishing Biofoundries and
Biomanufacturing hubs for enabling scale-up and validation of bio-based technologies of various start-
ups, innovations and industries. So far, over 600 beneficiaries have availed these facilities. In addition, a
pipeline of discovery led and bridging the gap research and development across thematic verticals
including bio-based chemicals and enzymes, functional foods and smart proteins, precision
biotherapeutics, climate-resilient agriculture, carbon capture and utilization, and marine and space
biotechnology is also being implemented. Together these will foster Make-in-India initiative for the
Biotech sector and contribute to the bioeconomy growth. The initiative has so far mobilized investment
commitment from private sector to the tune of Rs. 602.09 Cr.
This information was given by the Minister of State (Ind. Charge) Science & Technology; Earth Sciences
and Minister of State PMO; Personnel, Public Grievances and Pensions; Atomic Energy, Space Dr.
Jitendra Singh in a written reply in Rajya Sabha today.
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