Parliament Question: Promotion of integrative cancer care through Ayush

GOVERNMENT OF INDIA MINISTRY OF AYUSH RAJYA SABHA UNSTARRED QUESTION NO. 2724 TO BE ANSWERED ON 17th MARCH 2026 Promotion of integrative cancer care through Ayush 2724. Dr. Bhim Singh: Will the Minister of Ayush be pleased to state: (a) whether research is being conducted on medicines for the treatment of cancer and diabetes (sugar) through Ayurvedic, Siddha, Unani and other traditional medical systems with the aim of developing remedies that have minimal side effects and effectively address the root cause of the disease, if so, the details of the major research conducted so far along with the findings thereof; and (b) whether the medicines developed based on these researches have been approved for scientific evaluation, clinical trials and public use, if so, the number of such medicines currently being used in treatment and the benefits received by patients therefrom? ANSWER THE MINISTER OF STATE (IC) OF THE MINISTRY OF AYUSH (SHRI PRATAPRAO JADHAV) (a) Yes. Ministry of Ayush through its Research Councils namely; Central Council for Research in Ayurvedic Sciences, Central Council for Research in Homoeopathy, Central Council for Research in Siddha, Central Council for Research in Unani Medicine and National Institutes namely; All India Institute of Ayurveda and Institute of Teaching and Research in Ayurveda are undertaking research and healthcare activities related to cancer and diabetes through respective systems of medicine. Details of the research projects by the respective Research Councils /National Institutes are at the Annexures (I-V).Further, Ministry of Ayush through Central Sector Scheme -Ayurgran Scheme and Ayurswasthya Yojana provides financial assistance for research on cancer and diabetes. Details are at the Annexures VI. (b) All scientific evaluations and clinical trials are conducted following due procedures, including approvals from the Institutional Review Board (IRB) and Institutional Ethics Committee (IEC), and in accordance with applicable regulatory and ethical guidelines. Further, the Ayurveda, Siddha and Unani Medicines used for clinical purposes in Ayush institutions are primarily classical formulations mentioned in the respective pharmacopoeias and classical texts of the systems of medicine which are published in the respective pharmacopoeias and are described in classical texts and have been in continuous clinical use by Ayurveda, Siddha and Unani physicians. Scientific evidence of clinical efficacy and safety of approximately 182 classical Ayurveda formulations for 40 disease conditions have been generated by Central Council for Research in Ayurvedic Sciences among them 08 classical formulations and 02 coded formulations have been tested in Diabetes. For cancer, 02 coded formulations have been tested. Moreover, 02 coded formulations and 06 classical formulations have been tested in pre-clinical setups. Similarly, in the Homoeopathy system, medicines are prescribed based on the totality of symptoms and individualized treatment principles. The medicines used are those listed in the Homoeopathic Pharmacopoeia of India (HPI) published by the Government of India, which lays down standards for the quality, preparation, and use of homoeopathic medicines. Homoeopathic medicines developed through research have also undergone scientific evaluation and clinical studies. *****Annexure-I Details of research projects undertaken by Central Council for Research in Ayurvedic Sciences (CCRAS) on Cancer and Diabetes S.No Title of the project Participating institute Clinical research studies 1. A Pilot Study Evaluating Quality of Life with AYUSH AIIMS, New Delhi QOL – 2C in Patients of Local Non-Metastatic Breast Cancer Treated with Adjuvant Chemotherapy/Radiotherapy and Correlating it with Molecular Marker 2. Evaluating Quality of Life with Ayush QOL 2C in St. John’s Medical College, Patients of Non-Metastatic Breast Cancer as an Bengaluru Adjuvant to Chemotherapy 3. Effect of “Ayush QOL-2C” (Ayurvedic coded drug) Bhagwan Mahaveer Cancer in stage III & IV Non-Small Cell Lung Cancer to Hospital & Research centre, prevent side effects of Chemotherapy – A Randomized Jaipur Phase II Feasibility & Tolerability study 4. A phase II trial to study efficacy, toxicity and CARI, Mumbai in immunomodulatory effect of Carctol-S in high grade collaboration with TMC, serous epithelial ovarian cancer at first serological Mumbai relapse 5. Assessment of Prakriti (Ayurvedic body constitution) CARI, Mumbai in of patients with Cervical and Ovarian cancers. collaboration with Tata Memorial Hospital (TMH), Mumbai. 6. Study of Association between Prakriti and Outcomes CARI, Mumbai in of early and locally advanced breast cancer. collaboration with ACTREC, TMC, Mumbai 7. A Cross-sectional study of Cancer KAP among CARI, Mumbai Ayurveda and Allopathic fraternity 8. Ayurveda Interventions for Cancer: Systematic CARI, Mumbai Review, Meta-analysis; and Revival, Documentation, Validation and analysis of data from practitioners, institutes 9. Ayush ICMR-Advanced Centre for Integrative Health Ayush ICMR collaboration: Research (AI-ACIHR) in Cancer Care at AIIMS AIIMS, Nagpur Nagpur. 10. An open label parallel arm randomized controlled trial CARI, Mumbai in to assess the efficacy of ayurvedic medicines in the collaboration with AIIMS management of Oral submucosal fibrosis in a tertiary Nagpur care hospital at central India11. An evaluation of safety, Efficacy and treatment Indian Dental association Adherence of Gandoosha oral oil Retention Procedure and CCRAS-CARI on Oral dental Health in apparently healthy adult Mumbai population -An assessor blind exploratory Randomized controlled study. 12. Clinical Evaluation of Saptavimshatika Guggulu and CARI Bhubaneswar Haridra Churna in the management of Type II RARI, Jaipur Diabetes Mellitus RARI, Mandi 13. Clinical evaluation of Nisha Amalaki and CARI, Guwahati Chandraprabha Vati in the management of Type II RARI, Nagpur Diabetes Mellitus (Madhumeha) CARI, Delhi RARI, Ahmedabad 14. Clinical evaluation of Nisha Katakadi Kashaya and ALRARI, Chennai Yashada Bhasma in the management of Type II RARI, Vijayawada Diabetes Mellitus (Madhumeha) NARIP, Cheruthuruthy RARI, Mandi 15. Clinical evaluation of Gokshuradi guggulu and RARI,Gwalior Guduchi churna in the management of Madhumeha (Type II Diabetes Mellitus) 16. Clinical Evaluation of the Efficacy and Safety of CARI, Bengaluru Mamajjaka Ghanavati in Madhumeha (Type 2- CARI,Bhubaneswar Diabetes) RARI,Lucknow 17. A Randomized Placebo Controlled Prospective Phase RARI, Bengaluru II Clinical Study of an Ayurvedic Coded Drug 1. AIIMS, New Delhi ‘AYUSH-D’ in the management of Type 2 Diabetes 2. RAPA, Medical Mellitus as add on Therapy to Metformin College, Mumbai RGGPGAC, Paprola (Collaborative) 18. Efficacy of Ayurveda coded formulation Ayush D in CARI, Bengaluru the management of Type 2 Diabetes Mellitus-A SDM college of Ayurveda prospective multi-center randomized double blind Hassan placebo controlled clinical trial ( SMART 2.0) KSBMKAM, Belagavi 19. Efficacy of Ayurveda coded formulation Ayush 82 in RARI, Nagpur the management of Type 2 Diabetes Mellitus –A MGACHR, Wardha prospective randomized double blind placebo controlled clinical trial ( SMART 2.0) 20. Efficacy and safety of Ayurveda interventions for CARI, Mumbai Diabetes: A systematic review and Meta-Analysis Preclinical studies 21. Understanding Mechanistic role of CARAF and CARI, Mumbai in CAGHE as immunomodulatory and anti-cancer collaboration with compounds against pre-clinical models of Leukemia, ACTREC Mumbai lymphoma, Myeloma, Lung and Breast cancer.22. Understanding Mechanistic role of Carctol-S as an CARI, Mumbai in immunomodulatory and anti-cancer formulation collaboration with against Ovarian Cancer ACTREC Mumbai 23. Anticancer Potential and molecular mechanism of CARI, Kolkata in Rasa Sindhoor on ovarian cancer cells. collaboration with CSIR – IICB Kolkata 24. Evaluation of cytotoxicity, Pharmacokinetics, CARI, Kolkata in Anticancer activity, detailed molecular mechanisms of collaboration with CSIR – Bhallatakadi Modaka in In-vitro (2D & 3D culture) IICB Kolkata and In-vivo tumor xenograft models. 25. Anti-cancer activity of Chaulmoogra oil and CSMCARI Chennai Shwetha Sarshapa churna in the treatment of epidermal carcinoma of skin in experimental mice. 26. Evaluation of anti-cancerous potential, in-silico CARI, Kolkata in pharmacological analysis and molecular mechanism of collaboration with CSIR – Kanchanar guggulu in ovarian cancer µTumor IICB Kolkata spheroids, and in in vivo models. 27. Chemo preventive Effects of Opuntia elatior Fruits CARI, Kolkata in Against Chemotherapy-Induced Toxicity in Ovarian collaboration with CSIR – Cancer Pre-Clinical Models. IICB Kolkata 28. Study of selected Ayurvedic herbs for their anti- RARI, Gwalior angiogenic potential and toxicity profile in zebrafish embryo model for cancer management. 29. Assessment of Anti- Aging, Antimutagenic and cancer CARI, Mumbai in chemoprevention potential of Swarna Bhasma in collaboration with SSPU Drosophila Melanogaster Pune 30. Preclinical study on the efficacy, safety, and toxicity of RRAP CARI, Mumbai in Swarna Prashan regimen as adjunct therapy in collaboration with ICMR- Pediatrics acute lymphoblastic leukemia NIRRCH, Mumbai 31. Screening of medicinal plants on Anticancer Activity RARI Pune Other activities 32. International Cooperation with Office of Cancer Complementary and Alternative Medicine (OCCAM), National Cancer Institute (NCI). 33. Setting up of Integrative oncology facility at Tata Memorial Hospital (TMH), Mumbai. 34. Integration of AYUSH systems in the National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases & Stroke (NPCDCS) 35. CCRAS has contributed to the development of Standard Treatment Guidelines on Management of Metabolic Disorders in Ayurveda System of Medicine.Annexure-II Research Studies undertaken by Central Council for Research in Homoeopathy (CCRH) Research studies on Cancer: Fundamental and Basic Research: Ongoing: 1. Role of Silicea in cancer regression: A mechanistic study - Bose Institute, Kolkata, West Bengal. 2. Studies of homoeopathic medicines as nano-formulations in application to colon cancer therapy and insides into cancer cell death- JIS University, Kolkata. 3. Determination of the mechanism of action of clinically effective homoeopathic formulation in lung malignancies, Cochi University of Science and Technology. 4. Deciphering the molecular mechanisms of different homoeopathic remedies to overcome stemness in chemo-resistant triple negative breast cancer cells by targeting the miRNA circuitry: Phase 1 Approach- Jadavpur University, Kolkata. 5. Efficacy assessment of homoeopathic medicines on stratified epithelial cancer growth and gene expression profiles in cellular models: A multimodal approach- IIEST, Shibpur, Howrah. 6. Identification of homoeopathic formulations with anti-cervical cancer and anti– HPV activity (phase II): Assessment of Berberis Aquafolium and Berberis vulgaris In-vivo-A Pilot Study Comparing Cancer Cells and Normal Pbmcs from Non-Malignant Individuals.- University of Delhi, Delhi 7. Molecular characterization of Homoeopathic Medical Impact on Cervical Cancer Progression-IIEST, Shibpur Concluded: 1. Green synthesis of silver Nanoparticles using various plant based Homeopathic Mother tinctures and evaluation of the efficacy of the Homeopathic drug capped Silver Nanoparticles as potential anti-bacterial, anti-oxidant, anti-inflammatory and anticancer agents; Indian Institute of Engineering Science and Technology, Shibpur 2. In Vitro Assessment of Homeopathic Potencies of Hydrastis canadensis on Hormone- Dependent and Independent Breast Cancer. Homeopathy 2020; 109(04): 198-206 3. Contribution of ROS p53 feedback loop in thuja induced apoptosis of mammary epithelial carcinoma cells. Oncology Reports 2014 Jan 24.(Bose Institute, Kolkata) 4. Calcarea carbonica induces apoptosis in cancer cells in p53-dependent manner via an immuno-modulatory circuit. BMC Complementary and Alternative Medicine 2013; 13:230 (Bose Institute, Kolkata) 5. Sulphur alters NFκB-p300 cross-talk in favour of p53-p300 to induce apoptosis in non- small cell lung carcinoma. International Journal of Oncology 2015 June 22. (Bose Institute, Kolkata) 6. Evaluation of Therapeutic Potential of Selected Plant-Derived Homeopathic Medicines for their Action against Cervical Cancer. (Delhi University) Homeopathy 2023; 112(04): 262- 274. 7. Impact of homoeopathic medicines on Breast and Prostate cancer (AMITY University). In Vitro Assessment of Homeopathic Potencies of Hydrastis canadensis on Hormone-Dependent and Independent Breast Cancer. Homeopathy. 2020 Nov;109(4):198-206. doi: 10.1055/s-0040-1709668. Epub 2020 Jul 1. PMID: 32610349. 8. “Identification of Homoeopathic Medicines with AntiCervical Cancer and AntiHPV Activity: Phase1 :InVitro Study”, Homeopathy 2023; 112(04): 262-274 Clinical Research Ongoing: 1. A pilot study evaluating role of Homoeopathic medicine in non-small lung Cancer patients as adjuvant treatment to chemotherapy/ radiotherapy and correlating with Molecular Profiling (Department of Biotechnology, Ministry of Science & Technology, GoI, New Delhi), at AIIMS New Delhi. 2. Management of Chemotherapy and radiotherapy induced Oral Mucositis head and neck cancer with add on homoeopathy to standard care versus the standard care- A Randomized Controlled Clinical Trial, MAIDS, New Delhi. 3. A multicentric, double blind, randomized, placebo-controlled, phase III study to evaluate the role of potentised (tautopathy) form of chemotherapy in patients to determine the reduction in the pre-identified side-effects of non-Potentised Chemotherapy Drugs Cisplatin, Docetaxel, Paclitaxel, Carboplatin, Epirubicin, Gemcitabine, Cyclophosphamide and Adriamycin on cancer patients to enhance tolerance to chemotherapy regimen, Apollo Hospital and VS Hospital, Chennai. Concluded: 1. Phase II study to assess the safety and efficacy of using potentised form of chemotherapy, Apollo Hospital, Chennai 2. Evaluation of homoeopathy on side effects of chemotherapy in cancer patients, at Kolkata, Marwari Hospital. 3. Clinical evaluation of homœopathic medicines along with Iscador therapy in managing malignant diseases. CCRH. CR Studies series III, 2010, pg. 24-35. 4. Homoeopathic treatment as an add-on therapy for Pain Management in Cancer Patients: A Prospective, Randomized, Exploratory study (Dr. B.R.A. IRCH, AIIMS, New Delhi). Research studies on Diabetes Fundamental and Basic Research: Concluded studies: 1. Pancreatic beta-cell regeneration: a novel anti-diabetic action of Cephalendra indica mother tincture. British Homoeopathic journal 1988; 77(3): 147-151. 2. Effect of homeopathic preparations of Syzygium jambolanum and Cephalandra indica on gastrocnemius muscle of high fat and high fructose-induced type-2 diabetic rats: Homeopathy. 2013 Jul;102(3):160-71. Clinical Research: Ongoing: 1. Efficacy of Syzygium jambolanum mother tincture in management of type II Diabetes mellitus: A double-blind, randomized, placebo-controlled trial. 2. Investigating the impact of Homeopathic therapy on Metabolic Control and Systemic Inflammatory Markers in Patients of Stage III & IV Periodontitis with Diabetes: A Randomized Multi-Arm Clinical Trial.Concluded: 1. A prospective multi-centric open clinical trial of homeopathy in diabetic distal symmetric polyneuropathy. Homeopathy2013;102(2):130-8. 2. Management and homoeopathic treatment of peripheral vascular disease in relation to diabetes mellitus. CCRH Quarterly Bulletin, 1995; 17(3&4):10-6. 3. Rhus Aromaticus in the management of Diabetes mellitus. Clinical Research Studies- Series II. New Delhi: CCRH; 2009:21-7. 4. Role of Cephalandra indica Q in the management of Diabetes Mellitus as an add-on medicine along with conventional anti diabetics. Indian Journal of Research in Homœopathy 2008; 2(3):22-7. 5. Effects of Homoeopathic intervention in pre-diabetes (EHIP): An open label randomized controlled exploratory trial. 6. Practice, prescription habits, experience and perception of Indian homeopathic practitioners in treatment of diabetes mellitus: An online observational study. Journal of Ayurveda and Integrative Medicine 14 (2023) 100787 7. Calendula mother tincture vs normal saline for ulcer dressing as an add-on to Individualized Homoeopathic Intervention in the management of Diabetic Foot Ulcer: A Randomized Controlled Pilot Study. Indian J Res Homoeopathy 2020;14:233-41. 8. A Prospective Observational Study to Ascertain the Role of Homeopathic Therapy in the Management of Diabetic Foot Ulcer. American Journal of Homeopathic Medicine 2011; 104(4):166-76. 9. Efficacy of homoeopathic treatment for diabetic distal symmetric polyneuropathy: A multicentric randomised double-blind placebo-controlled clinical trial. Explore (NY). 2020 May 22:S1550-8307(20)30163-4.Annexure-III Research studies related to various types of Cancer by Central Council for Research in Unani Medicine (CCRUM) ➢ A study to evaluate of the anticancer potential of Unani Pharmacopoeial formulation, ‘Dawa-ul-Kurkum’ was conducted on human liver cancer cells and findings depict that the formulation is effective in restoring the damage at the genetic level due to cancer. ➢ Another study was done on delineating the Anti- Cancer potential and the mechanism of action of Unani medicinal formulation Itrifal-e-Aftimoon in Chronic Myelogenous Leukemia was carried and the formulation is effective as an adjuvant therapy with Imatinib for the better management of CML. ➢ A study was also to evaluate the antioxidant and anticancer effects of Unani Medicine (Qurs-e-Mafasil ladeed, Safoof-e Barang, UNIM-HC-I) against hepatocellular carcinoma (HCC). The in-vitro cytotoxicity assessment revealed that Nigella sativa, Cuscuta reflexa, and Chicorium intybus exhibited promising inhibitory effects on cancer cell proliferation with IC₅₀ values comparable to the standard drug. ➢ Phytochemical standardization and evaluation of anti-cancer and immunomodulatory activity of Unani formulation, Itrifal Ghudadi. IGaq significantly reduced cell viability in cervical, breast and oral cancer cell lines. ➢ A study is being was conducted on combining Unani formulations and nutraceuticals with standard chemotherapeutic agents (5-FU and OXP) and it was observed that the Unani formulations enhances anticancer efficacy in CRC while potentially reducing toxicity and resistance. ➢ The cytotoxic effects of the different Majoon Najah extracts showed promising effect against liver carcinoma ➢ A study conducted on novel Unani dispersible tablets was conducted and the results demonstrated that polyherbal formulation induces cell apoptosis Research studies related to Diabetes mellitus: ➢ A study was conducted to compare the efficacy and safety of coded Unani formulation UNIM-221 with Metformin in the patients of Dhayābīṭus Sukkarī Qism-i Thāni (Diabetes mellitus Type II). ➢ The study drug was found safe and effective. Another validation study to evaluate the safety and efficacy of Qurs Ziabetus khas was conducted and the study drug was found safe and effective. ➢ Investigation on pharmacodynamic and pharmacokinetic interaction of Unani plants Tinospora cordifolia and Eugenia jambolana with hypoglycaemic drug. ➢ Assessment of the effect of Unani formulation loaded nanoparticle tablets against Streptozotocin-induced Diabetes. ➢ Structural characterization, pharmacokinetics, pharmacodynamic and herb-drug interactions of major constituents of compound Unani formulation for diabetes ➢ Novel Unani Medicine infused Organic Oil based in-soles for diabetic foot care ➢ Anti-diabetic and Immune-modulatory effect of Unani formulation “Safuf-i-Dhayabitus’ ➢ Pharmacological Evaluation and Comparison of Anti-Diabetic Activity of the Novel Unani Formulation with Metformin In Experimental Model Of Diabetes➢ Effect of Selected Unani formulation on oxidative stress in patients with type 2 diabetes mellitus a randomized double-blind placebo controlled clinical trial ➢ Comparative study of Sugar free formulation of Jawarish Zarooni Sada with its traditional formulation against for the treatment of Diabetic Nephropathy ➢ Role of poly-herbal formulation on the bone’s ultrastructural, metabolic and biomechanical changes in Diabetic BALB/c miceAnnexure -IV Detail of the Research/Project for diabetes and Cancer taken by Central Council for Research in Siddha (CCRS) IMR Projects related to Cancer: 1. Evaluation of anticancer and Apoptosis-Inducing effect of Gowri Chinthamani Chenthuram (GCC) on human cancer cell lines 2. Clinical trial to evaluate the safety and efficacy of Siddha medicine nandhi mezhugu in stage 1 and 2 breast cancer patients. 3. Another project entitled "SIDDHAR-ONCO: A Siddha Literary and Field-Based Cancer Research Study". IMR Projects related to DM: 1. Evaluation of anti-diabetic activity of Argyreia sericea Dal zell against streptozotocin induced diabetes in Rat 2. Alternative therapy for Diabetic Retinopathy / cataract of Fluggea virosa in rats. 3. A pilot open single arm clinical trial to evaluate the efficacy of Sirupeelai Kudineer in Diabetic Nephropathy. 4. Observational Study to scientifically validate Siddha Diagnostic methods - Neerkuri, Neikuri with the prediction of disease prognosis using Machine learning Procedures and Early Diagnosis of Diabetes Mellitus using the Diagnostic Standards in Modern Medicine”. 5. In-process standardization of Velvanga Parpam (VP) A classical Siddha drug and a pilot study to evaluate its safety and therapeutic efficacy in Madhumegam (Type II Diabetes mellitus) EMR Projects related to DM: Ameliorative potential of D5 Choooranam in Streoptozotocin induced Diabetes Retinopathy.Annexure-V List of ongoing Research projects on Cancer in Integrative Oncology at All India Institute of Ayurveda, (AIIA) New Delhi S. Title Status Outcome No. Extra Mural Research- EMR 1. Clinical validation of synergistic effect of Ongoing Yet to conclude vardhman pippali rasayan along with conventional treatment after unravelling its complex molecular mechanism of action in Breast cancer: From Experimental model to Clinical trial in collaboration with AIIMS 2. Clinical Trail to Evaluate the safety and Ongoing Yet to conclude Efficacy of Siddha medicine Nandhi Mezahugu in Stage 1 &2 BREST Cancer Patients in collaboration with Central Council for Research in Siddha Intra Mural Research- IMR 3. An open-label, two-arm, exploratory Completed Vardhman pippali randomised controlled trial to evaluate the rasayan was found to effect of Vardhman pippali rasayan as an add- improve quality of life on therapy in the management of non-small of lung cancer patients cell Lung cancer in Collaboration with & was well tolerated AIIMS. by patients 4. Ayurveda Intervention for Chemotherapy In the Yet to start induced Myelosuppression process of approvals PhD Studies 5. A prospective observational cohort study on Ongoing Yet to conclude clinical presentation, Ayurvedic understanding, patient intentions, and treatment outcomes in Hepatobiliary Cancers and A clinical pilot study to assess the outcomes of Ayurveda Interventions in Hepatocellular Carcinoma. Post Graduate Studies 6. A prospective observational cohort study on Ongoing Yet to conclude clinical presentation, Ayurvedic understanding, patient intentions, and treatment outcomes in Oral Cancers Research studies related to the management of Prameha/Madhumeha (Diabetes Mellitus) through Ayurveda are being conducted at various departments under Post Graduate research programmes. These studies aim to evaluate the efficacy of Ayurvedic formulations,Panchakarma procedures, dietary regulations and lifestyle interventions in improving glycemic control and reducing disease complications with minimal side effects. n addition to the above- mentioned research studies, an Ayurvedic treatment protocol for the management of Prameha/Madhumeha (Diabetes Mellitus) has also been developed based on classical Ayurvedic principles and research findings. The protocol includes Ayurvedic medicines, Panchakarma procedures, dietary regulations (Pathya Ahara), and lifestyle modifications (Vihara) aimed at improving glycemic control and addressing the root cause of the disease with minimal side effects. The details of major research studies conducted in recent years are given below: • IMR Project S. Title Conducted Status Drug Used No. By- 1. Evalation the efficacy of diabetic Dr. Raja ram Ongoing Gudmar specific diet and life style modification in Mahto Churna comparison with ayurvedic Shodhan- Nishamalki Rasayan in the management of Churna Madhumeha (Diabetes mellitus) Gokshura Churna Gokshrsdi Guggulu 2. Evaluate the correlation of changes in Dr. Raja Ram Ongoing Triphaladi Nadi, Tongue and Face with Diabetes Mahto Kwath parameter among Diabetes (Type 2) Dr. Jonah S. patients- An Exploratory Study Dr. Rama Nishakatakadi Kant Yadava Kwath 3. Prevalance of Musculoskeletal Dr. Raja Ram Ongoing Dysfunction in Patients of Prameha Mahto (Diabetes Mellitus Type 2)S. Research Protocol / Topic Year Conducted by Key Findings / Medicine used in No. (Doctor & Outcome IPD/OPD Department) 1 A Conceptual study on 2019– Dr. Aishwarya Ayurvedic diet Abhya Ghan Vati Dwividhopkarniya Adhyaya 2022 – Department regulation, lifestyle of Acharya Vagbhatt and of Samhita modification and clinical study to assess the Siddhanta Abhaya Ghan Vati cumulative effect of showed improvement Aptarana with Abhaya Ghan in symptoms of Vati and Pathya Ahara- Diabesity and Vihara on Santarpanotha metabolic parameters. Vyadhi w.s.r. to Sthula Pramehi (Diabesity) 2 Role of Rasa Sevan Karma 2019– Dr. Sheetal – Proper sequence of (consumption order of 2022 Department of taste consumption tastes) of food in proper Samhita improved digestive functioning of Jatharagni Siddhanta function and helped and its impact on post- regulate post-prandial prandial glycemia blood glucose levels. 3 Ayurveda protocol for 2019– Dr. Kundan – Ayurvedic therapeutic Nishakatakadi management of 2022 Department of protocol demonstrated Kashya Prameha/Madhumeha with Kayachikitsa improvement in blood Mamajjaka Ghan vati special reference to Type-2 glucose levels and Gokshuradi Diabetes Mellitus using clinical symptoms. guggulu different dosage patterns 4 Effect of Vaman Karma and 2019– Dr. Nishant Vaman karma with Triphal Churna Triphala Churna with Madhu 2022 Malhotra – Ayurvedic Guduchi Churna on gut microbiota and Department of intervention showed metabolites in Prameha w.s.r. Panchakarma beneficial changes in to Type-2 Diabetes Mellitus gut microbiota and metabolic parameters. 5 Antidiabetic effect of 2018– Dr. Kajal – Pre-clinical study Gojihva Extract Swarasa and hydro-alcoholic 2021 Department of demonstrated extract of Gojihva in Type-2 Dravyaguna significant reduction Diabetic Wistar Rats in blood glucose levels in experimental models.6 Efficacy of Aardra & 2018– Dr. Niranjan Aadra Guduchi ghan Guduchi Ghan Shushka Guduchi in 2021 Ram – vati showed Vati management of Madhumeha Department of significant (Type-2 DM) SRPT hypoglycemic effect and symptomatic improvement. 7 Comparative effectiveness 2018– Dr. Charu Ayurvedic Nishamlaki Tab of Ayurvedic management 2021 Sharma – interventions along and conventional standard Department of with standard care Sarvamehahara Kashya Ghana care in Gestational Diabetes SRPT improved glycemic Vati Mellitus control and maternal health outcomes. 8 Cross-sectional study on the 2018– Dr. Meenakshi Study correlated breakup model of 2021 Sharma – Ayurvedic disease Shatakriyakala in Prameha Department of stages with clinical w.s.r. to Type-2 Diabetes Rog Nidan and biochemical Mellitus Evam Vikriti markers of diabetes. Vigyan 9 Efficacy of Rohitakadi 2018– Dr. Mythri Rohitakadi Churna Triphladi granules Churna along with 2021 H.S. – along with Triphaladi Rohitakadi churna Triphaladi Granules in Department of Granules is more management of Madhumeha Kayachikitsa effective then Triphaladi granules 10 Study on Ojas and 2017– Dr. Durgesh Study highlighted prevalence of Oja Kshaya in 2020 Senthiya – association between patients of Madhumeha Department of Oja Kshaya and Ayurveda severity of Samhita and Madhumeha. Siddhanta 11 Study of Swabhavoparam 2017– Dr. Pratigya Avoidance of Phalatrikadi Vada (Nidana Parivarjana) in 2020 Chauhan – etiological factors Kwath newly diagnosed Department of showed improvement Madhumeha Ayurveda in disease progression Samhita and and glycemic control. Siddhanta 12 Study to assess Ojas Dushti 2017– Dr. Sidhartha Findings indicated in Madhumeha and 2020 Kumar – correlation between evaluation using Department of Ojas Dushti and immunological marker IgG Rog NidanEvam Vikriti immunological Vigyan markers. 13 Comparative clinical trial of 2017– Dr. Asha The administration of Darvyadi Ghrita Darvyadi Ghrita vs Darvyadi 2020 Malviya – Darvyadi Ghrita in Kashaya in Vatapradhana Department of vata pradhan Prameha Darvyadi Kashya Prameha Kayachikitsa gives better result in subjective parameters.and Darvyadi Kashya mild significant reduction in FBS and PPBS 14 Efficacy of D4 combination 2017– Dr. Dimpal Adjunct Ayurvedic D4 Combination along with ongoing 2020 Gill – therapy improved (Jamunbeej, conventional medicine in Department of glycemic control when Gudmar patra,Giloy,Ngar Type-2 Diabetes Mellitus Kayachikitsa used with motha churna) conventional treatment. 15. A Comparative clinical trial 2021- Dr. Kartar The ayurvedic Vidangadi loha on the efficacy of Vidangadi 2024 Singh Bansal regimen administrated Loha and Phalatrikadi (Ph.D) to Group B presents a Phaltrikadi Ghanvati with and without promising avenue for Ghanvati the primer administration of enhancing the Virechan Karma in treatment of Madhumeha Madhumeha (obese diabetic )Annexure-VI The details of project funded for research on Cancer & Diabetes under Research and Innovation in Ayush component of Ayurgyan Scheme: S.No. Name of Institution Title of Project State Amount approved 1 Department of Pharmacological Kerala Rs.52,34,697/- Veterinary evaluation of Pharmacology & homoeopathic drugs in Toxicology, College of breast Veterinary & Animal cancer cell lines. Sciences (CVAS), Mannuthy, Kerala Veterinary and Animal Sciences University, Pookode, Wayanad 2 National Isntitute of Gomutra Ark as a potent Odisha Rs.58,80,780/- Technology, Rourkela, anti-cancer agent for the Odisha. treatment of Oral SquamousCell Carcinoma - Molecular Mechanism underlying its anti-cancer effect. 3 Asthagiri Herbal Process Standardization Tamil Nadu Rs.68,74,110/- Research Foundation and Perungudi Industrial exploration of novell Estate Perungudi Saarapathangam Chennai Preparation for its role in the management of oropharyngeal cancer 4 SDM College of Medical Effect of Yoga on Karnataka Rs. 42,36,898/- Sciences & Hospital, Endothelial Function and Manjushree Nagar, Vascular Aging in Sattur, Dharwad, Individuals with Type-2 Karnataka Diabetes (Yoga V-Age): A Randomized Controlled TrialThe details of project funded for research on Cancer & Diabetes under center of excellence component of Ayurswasthya Yojana Name of Fund released Approved State/UT Title of the Project Organization/Institute in Rs. amount in Rs. CoEs with Cancer project Tata Memorial Centre, Maharashtra Centre of Excellence for 3,94,10,182/- 9,06,91,262/- (TMC) Mumbai Discovery and Development of Ayush Medicine for Cancer Care Arya Vaidya Sala, Kerala Setting up CoE in 5,31,56,136/- 6,64,45,170/- Kottakkal Cancer Research Arya Vaidya Sala, Kottakkal CoEs on Diabetes Mellitus Indian Institute of Karnataka Centre of Excellence in 7,63,93,188/- 9,99,96,500/- Science, (IISC) Diabetes and Metabolic Bangalore Disorders Central Ayurveda Karnataka Centre of Excellence in 7,24,80,400/- 7,24,80,400/- Research Institute Research and Clinical (CARI) Bengaluru Services for Madhumeha (Diabetes Mellitus)