Home India Ministry of Health and Family Welfare Classification of Medical Device pertaining to Software unde...
Date: 2021-09-13 Category: Not Applicable State: Union Government Country: India

Classification of Medical Device pertaining to Software under the provisions of Medical Devices Rules 2017

Issued by Ministry of Health and Family Welfare · Central Drugs Standard Control Organization

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Executive Summary & Key Takeaways

What it means

  • This notice from the Drugs Controller General (India) provides a classification of various medical devices pertaining to software based on their risk.

Key Changes

  • The notice classifies 60 different software-based medical devices into risk Classes A, B, or C.
  • Class A includes devices like 'Continuous Glucose Monitor Retrospective Data Analysis Software'.
  • Class B includes devices like 'Continuous Glucose Monitor Secondary Display', 'Insulin Pump Secondary Display', 'Multivariate Vital Signs Index', 'Electrocardiograph Software for home use', 'Photoplethysmograph Analysis Software for home use', 'Colon Computed Tomography System, Computer Aided Detection', 'Lung Computed Tomography System, Computer-Aided Detection', 'Chest X-Ray Computer Aided Detection', 'Radiological Assisted Detection/Diagnosis Software For Fracture', 'X-Ray Angiographic Imaging Based Coronary Vascular Simulation Software Device', 'Automated Radiological Image Processing Software', 'Image Acquisition And/Or Optimization Guided By Artificial Intelligence', 'Chairside dental CAD/CAM unit', 'Software for using with mammography-combined diagnostic X-ray system', 'Software for public thoracic and abdominal health screening diagnostic X-ray system', 'Software for visual evoked response stimulator', 'Software for auditory evoked response stimulator', 'Software for pulmonary exercise stress monitoring system', 'Software for ECG recorder with real-time analysis', 'Software for film-recorded digital radiography', 'Software for dye dilution cardiac output calculator', 'Software for urodynamic measurement system', 'Software for vestibular function caloric stimulator', 'Surporting software for external fixators treatment plan', 'Diagnostic supporting software for diabetes', 'Quantitative calculation software for IGC test', 'Analyzing software for hemodynamics or cardiac function', 'Supporting software for root canal treatment'.
  • Class C includes devices like 'Insulin Pump Therapy Adjustment Calculator For Healthcare Professionals', 'Coronary Vascular Physiologic Simulation Software', 'Angiographic Coronary Vascular Physiologic Simulation Software', 'Software For Visualization Of Vascular Anatomy And Intravascular Devices', 'Orthodontic Software', 'Dental Abutment Design Software For Dental Laboratory', 'Neuropsychiatric Interpretative Electroencephalograph Assessment Aid', 'Normalizing Quantitative Electroencephalograph Software', 'Index-Generating Electroencephalograph Software', 'Source Localization Software For Electroencephalograph Or Magnetoencephalograph', 'Automatic Event Detection Software For Polysomnograph With Electroencephalograph', 'Automatic Event Detection Software For Full-Montage Electroencephalograph', 'Computerized Cognitive Assessment Aid For Concussion', 'Computerized Behavioral Therapy Device For Psychiatric Disorders', 'Brain Injury Adjunctive Interpretive Oculomotor Assessment Aid Device', 'Fertility Diagnostic, Contraceptive, Software Application', 'Diabetic Retinopathy Detection Device', 'Computer-Assisted Diagnostic Software For Lesions Suspicious For Cancer', 'Burn Resuscitation Decision Support Software', 'Software, Similarity Score Algorithm, Tissue Of Origin For Malignant Tumor Types', 'Software for peritoneal dialysis treatment planning', 'Software for radiation planning', 'Software for radiotherapy QAQC planning', 'Software for ophthalmic surgery treatment planning', 'Software for active implanted device control', 'Information collating software for radiotherapy', 'Software for gene variants analysis (for cancer genome profiling)', 'Supporting software for differential diagnosis with endoscopic imaging', 'Ventilator, software'.
  • Note 1 states that software driving or influencing a device falls into the same risk class as the device.
  • Note 2 states that any add-on to the same software will be treated as the same risk class.

Impact Analysis

Medical Device Manufacturers

  • Action Item: Review product portfolio and classify devices according to this notice. Update regulatory strategy accordingly.

Healthcare Professionals

  • Action Item: Understand the risk classification of software-based medical devices used in clinical practice.

Regulatory Bodies

  • Action Item: Implement this classification in regulatory processes.

Key Entities Referenced

Drugs Controller General (India): The issuing authority for this notice, responsible for regulating drugs and medical devices in India. Central Drugs Standard Control Organisation (CDSCO): The national regulatory body for pharmaceuticals and medical devices in India. Medical Devices Rules 2017: The regulatory framework governing medical devices in India, which this notice references for classification.
Official Source Record View Original Source →
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Appendix-A File No. 29/Misc./03/2020-DC (198) Drugs Controller General (India) Directorate General of Health Services Central Drugs Standard Control Organisation FDA Bhawan, Kotla Road, New Delhi Notice Classification of Medical Devices Pertaining to Software Risk S.No Device Name Intended Use Class Continuous Glucose Continuous glucose monitor retrospective data analysis software is intended to Monitor 1 analyze and correlate retrospective data from a continuous glucose monitoring A Retrospective device. Data Analysis Software Continuous Glucose The purpose of the continuous glucose monitor secondary display is to notify 2 Monitor another person, the follower, of the patient's continuous glucose monitoring B Secondary system sensor glucose information in real time. Display Insulin Pump The purpose of the insulin pump secondary display is to notify another person 3 Secondary B of the patient's insulin pump usage information in real time. Display Insulin Pump An insulin pump therapy adjustment calculator for healthcare professionals is Therapy intended to recommend insulin pump therapy parameter adjustments (e.g., Adjustment 4 basal rate, insulin to carbohydrate ratios, insulin sensitivity factors) based on C Calculator For data from external devices, including continuous glucose monitors. The device Healthcare is software with a graphical user interface. Professionals Coronary A coronary vascular physiologic simulation software device is intended to aid in Vascular the identification of functionally significant cardiovascular disease by performing 5 Physiologic C offline analysis of pre-existing imaging data to simulate blood flow in the Simulation coronary vasculature. Software Multivariate Automated calculation of a summary index (or indices) based on several 6 Vital Signs individual measured vital sign inputs. Collects measured parameter inputs and B Index automates the calculation of a summary index based on those parameters Electrocardiogr Device intended for home use which creates, analyzes, and displays 7 aph Software electrocardiograph data, and can provide information for identifying cardiac B for home use. arrhythmias. Photoplethysm ograph Photoplethysmograph analysis software device for home analyzes of 8 Analysis photoplethysmograph data and provides information for identifying irregular B Software for heart rhythms. This device is not intended to provide a clinical diagnosis. home use. Angiographic Coronary An angiographic coronary vascular physiologic simulation software device is Vascular 9 intended to aid in the identification of functionally significant cardiovascular C Physiologic disease. Simulation Software 1 of 7Software For Visualization Of Vascular Visualization and measurement of blood vessels and intravascular devices for 10 C Anatomy And preoperational planning. Intravascular Devices Orthodontic The device is software that is to be used for the diagnosis and treatment 11 C Software planning of orthodontic patients and conditions. Dental The software device is intended to aid in the restoration of chewing function by Abutment allowing a dental laboratory or dental clinician to design the patient-specific Design 12 component of a dental abutment (i.e. abutment collar and abutment post) and C Software For CAM or create that component at a dental office or dental laboratory following Dental the directions of the dental implant system. Laboratory Diagnostic Software, K- Nearest The device is intended to suggest a systemic autoimmune disease association 13 Neighbor as an aid for differential diagnosis to be evaluated in conjunction with clinical B Algorithm, findings and other laboratory tests. Autoimmune Disease Neuropsychiatri c Interpretative Electroencepha Intended as an aid to provide an interpretation of the patient's neuropsychiatric 14 C lograph condition. Assessment Aid Normalizing Quantitative Post-hoc statistical analysis of electroencephalograph signals with comparison 15 Electroencepha C to a normative database for interpretation by a qualified clinical user. lograph Software Index- Generating Analyze electrical activity of the brain by transformation of 16 Electroencepha electroencephalograph signals into a dimensionless index number for use and C lograph interpretation by a qualified clinical user. Software Source Localization Software For Correlation of electrical activity of the brain using various neuroimaging 17 Electroencepha C modalities for source-localization lograph Or Magnetoencep halograph Automatic Event Automatically mark electroencephalograph and polysomongraph signals in Detection order to aid in identification of such events and annotation of prolonged PSG Software For 18 traces; Automatically calculate simple measures obtained from recorded signals C Polysomnograp (e.G. Magnitude, time, frequency and simple statistical measures of marked h With events); All output subject to verification by qualified clinical user Electroencepha lograph 2 of 7Automatic Event Automatically mark or identify electroencephalograph waveforms for spikes, Detection electrographic seizures, seizure-like events in order to aid in identification of 19 Software For C such events and help review and annotation of prolonged EEG traces; All Full-Montage output subject to verification by qualified clinical user Electroencepha lograph Computerized Cognitive 20 Assessment For use as an assessment aid in the management of concussion. C Aid For Concussion Ataxiagraph Device used to determine the extent of ataxia (failure of muscular coordination) With by measuring the amount of swaying of the body when the patient is standing 21 A Interpretive erect and with eyes closed and provides interpretation or clinical implication of Software the measurement. Computerized Behavioral The device is intended to provide cognitive behavioral therapy to treat Therapy 22 substance use disorder. The device is a software-based mobile app C Device For downloaded onto a smartphone. Psychiatric Disorders Brain Injury Adjunctive A traumatic brain injury eye movement assessment aid is a prescription device Interpretive 23 that uses a patients tracked eye movements to provide an interpretation of the C Oculomotor functional condition of the patients brain. Assessment Aid Device, Fertility Diagnostic, Designed to monitor and provide fertility information to prevent pregnancy 24 Contraceptive, C (contraception). Software Application Diabetic A retinal diagnostic software device is a software device that incorporates an Retinopathy 25 adaptive algorithm to evaluate ophthalmic images for diagnostic screening to C Detection identify retinal diseases or conditions. Device Colon Computed Tomography To assist radiologists in the review of multi-slice computed tomography (msct) 26 System, exams of the colon and highlight potential polyps that the radiologist should B Computer review. Aided Detection Lung Computed Tomography To assist radiologists in the review of multi-slice computed tomography (msct) 27 System, exams of the chest and highlight potential nodules that the radiologist should B Computer- review. Aided Detection Chest X-Ray Computer To assist radiologists in the review of chest radiographic images and highlight 28 B Aided potential nodules that the radiologist should review. Detection 3 of 7Computer- Assisted Diagnostic Assist clinical users in characterizing lesions identified on acquired medical 29 Software For C images Lesions Suspicious For Cancer Radiological Computer A radiological computer assisted detection and diagnostic software for Assisted suspected fracture is an image processing device intended to aid in the 30 B Detection/Diag detection, localization, and/or characterization of fracture on acquired medical nosis Software images (e.g. radiography, MR, CT). For Fracture X-Ray Angiographic X-ray angiographic imaging based coronary vascular simulation software device Imaging Based is a device that provides an image analysis tool to assess blood flow in the Coronary 31 coronary vascular system using X-ray angiographic imaging data. And yields B Vascular simulation-based metrics for certain cardiology applications which aid clinical Simulation user. Software Device Automated Radiological To provide automated radiological image processing and artificial intelligence 32 Image B based analysis tools. Processing Software Image Acquisition And/Or A radiological acquisition and/or optimization guidance system is a device that 33 Optimization is intended to aid in the acquisition and/or optimization of images and/or B Guided By diagnostic signals. Artificial Intelligence Burn Resuscitation The burn resuscitation decision support system (BRDSS) is intended for use in 34 Decision prediction of hourly fluid volume during initial 24 hours of burn resuscitation. It is C Support intended for patients who have greater than 20% total body surface area burn. Software Software, Similarity Score This test is intended to measure the degree of similarity between the RNA Algorithm, expression pattern in a patient?s fresh-frozen tumor and the RNA expression 35 Tissue Of patterns in a database of tumor samples for some common malignant tumor C Origin For types that were diagnosed according to then current clinical and pathological Malignant practice. Tumor Types Software for A software that performs prescription simulation of peritoneal dialysis based on peritoneal the results obtained from a peritoneal function test (PFT), a peritoneal 36 C dialysis equilibration test (PET) and a body composition analyzer. It supports treatment preparation of a dialysis treatment plan. Software for A software that calculates and displays the area to be treated with radiation and 37 radiation the internal dose distribution based on the results obtained with CT systems C planning etc. , and supports the radiotherapy planning. 4 of 7Software for A software that verifies the validity of the radiotherapy plan by recalculation of radiotherapy 38 the dose and the MU value calculated with the radiotherapy planning system C QAQC software and radiotherapy planning system. planning Software for ophthalmic A software for intended to aid ophthalmic surgical planning based on 39 surgery C measurement of the eye prior to the surgery. It simulates surgical results. treatment planning Software for active A software used to transmit one or more electrical operating characteristics 40 C implanted noninvasively to the active base unit and change the characteristics. device control Information A software that has function of collating the information such as irradiation collating parameter specified by a radiation planning software, and the condition that a 41 C software for radiotherapy equipment irradiates, on the occasion of the irradiation of X-ray in radiotherapy the radiotherapy. Software for gene variants A software for gene variants analysis which is designed to perform cancer 42 analysis (for genome profiling based on information of gene variants obtained from body C cancer genome tissue samples. profiling) Supporting A software, which is designed to process data obtained from an endoscopic software for image. The resultant data are provided for diagnostic, etc. It has functions to differential 43 output numeric values and graphs based on quantitative data such as C diagnosis with benign/malignant differentiation of lesion candidates, presenting candidates of endoscopic diagnostic outcomes, and stage of disease progression. imaging Chairside Intended for computer-aided design (CAD) or computer-aided manufacturing 44 dental B (CAM) of dental restorations. CAD/CAM unit Software for using with mammography- A software, which is designed to processes data obtained from a combined 45 B combined diagnostic mammography-radiography system. diagnostic X- ray system Software for public thoracic A software, which is designed to process data obtained from a thoracic and and abdominal abdominal public health screening diagnostic X-ray system. The resultant data 46 health B are provided for diagnosis, etc. This term may involve the recording media screening where the software are stored. diagnostic X- ray system Software for visual evoked A software, which is designed to process data obtained from a visual evoked 47 B response response stimulator. The resultant data are provided for diagnosis, etc. stimulator 5 of 7Software for auditory A software for medical device, which is designed to process data obtained from 48 evoked an auditory evoked response stimulator. The resultant data are provided for B response diagnosis, etc. stimulator Software for pulmonary A software, which is designed to process data obtained from a pulmonary 49 exercise stress B exercise stress monitoring system. monitoring system Software for ECG recorder A software, which is designed to process data obtained from an ECG recorder 50 B with real-time with real-time analysis. The resultant data are provided for diagnosis, etc. analysis Software for film-recorded A software, which is designed to process data obtained from a film-recorded 51 B digital digital radiography. The resultant data are provided for diagnosis, etc. radiography Software for dye dilution A software, which is designed to process data obtained from a dye dilution 52 B cardiac output cardiac output unit. The resultant data are provided for diagnosis, etc. calculator Software for urodynamic A software, which is designed to process data obtained from a urodynamic 53 B measurement measurement system. The resultant data are provided for diagnosis, etc. system Software for vestibular A software, which is designed to process data obtained from a vestibular 54 B function caloric function caloric stimulator. The resultant data are provided for diagnosis, etc. stimulator Surporting A software that analyzes information useful for bone fracture and for correction software for of bone deformities based on information collected from diagnostic X-ray 55 external B systems, etc. or based on information entered in a therapeutic apparatus, and fixators supports preparation of a treatment plan with external fixators. treatment plan Diagnostic A software that supports analysis and assessment of therapeutic effects of supporting 56 diabetes treatment by processeing information collected from a blood glucose B software for meter, etc into the data related to changes or trends in blood glucose levels. diabetes Quantitative A software that performs quantitative calculation of blood flow in relation to a calculation 57 brightness time change based on information obtained from video images of B software for indocyanine green angiography. IGC test Analyzing software for A medical device program that analyzes hemodynamics or cardiac function 58 hemodynamics based on information obtained from diagnostic imaging systems, etc. and uses B or cardiac the results for diagnosis. function 6 of 7Supporting A software for medical device, which is used to support preparation of a software for 59 treatment plan based on information collected from diagnostic imaging systems, B root canal etc. in the root canal treatment. treatment A data program designed for use in, or together with, a ventilator allowing it to Ventilator, 60 function according to the intended purpose. The software can be installed, or C software exchanged as an upgrade. Note 1 - As per clause (iii) of Part I of First Schedule of Medical Devices Rules 2017, Software, which drives or influences the use of a device, falls automatically in the same class. Note 2 - Any add-on to the same software will be treated as same risk class. 7 of 7

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