Home India Ministry of Health and Family Welfare Medical Device Alert date 14 June 2022...
Date: 2022-06-14 Category: Not Applicable State: Union Government Country: India

Medical Device Alert date 14 June 2022

Issued by Ministry of Health and Family Welfare · Central Drugs Standard Control Organization

Research with AI Agent Chat with Document Generate Summary Translate Helpful Share Add to Project Create Task

Executive Summary & Key Takeaways

What it means

  • The Central Drugs Standard Control Organization (CDSCO) has issued a medical device alert regarding the EEA Auto Suture Circular Stapler/ Loading unit with DST Series Technology (Staple), specifically the 25mm size, due to a potential defect where the staple guide may not be securely attached.
  • This issue could lead to the device transecting tissue without forming staples, resulting in potential complications such as delay of treatment, extended hospital stays, tissue injury, unintended radiation exposure, unexpected medical intervention, foreign body in patient, failure to anastomose, and hemorrhage.
  • India Medtronic Pvt. Ltd. has issued a Field Safety Notice regarding this issue.

Key Changes

  • The alert specifically concerns 25mm EEA Auto suture Circular Staplers with DST Series Technology, model numbers EEA25, EEAXL25, EEA2535, and EEAXL2535.
  • A voluntary Field Corrective Action (FCA) will be implemented to communicate the issue to all consignees who have received the affected product.
  • Consignees will be asked to confirm receipt of the FCA notification and return all unused affected product.
  • 2625 units were imported into India between June 2017 and February 2022.
  • 2408 units were supplied in India between June 2017 and May 2022.
  • The Field Safety Corrective Action (FSCA) commenced on May 13, 2022, by the product owner, and in India, it is expected to commence on May 25, 2022.
  • The proposed date of completion of FSCA is July 21, 2023.
  • CAPA2022-018332 was issued to investigate the root cause of the issue and implement corrective and preventive actions (CAPA).

Impact Analysis

Patients

  • Action Item: Hospitals and surgeons should immediately identify and quarantine affected staplers. Review recent surgical cases to determine if affected staplers were used and assess patients for potential complications.

Hospitals and Surgical Centers

  • Action Item: Implement a recall process to remove affected devices from inventory. Contact Medtronic for replacement devices. Develop a communication plan to inform surgical staff about the issue and the recall process.

India Medtronic Pvt. Ltd.

  • Action Item: Continue to execute the voluntary FCA, ensuring all consignees are notified and affected products are returned. Collaborate with CDSCO to ensure compliance with regulatory requirements. Finalize and implement CAPA to address the root cause.

CDSCO

  • Action Item: Monitor the progress of the FSCA and ensure Medtronic's compliance. Communicate with hospitals and healthcare professionals to raise awareness about the issue. Review Medtronic's CAPA to ensure it adequately addresses the root cause.

Key Entities Referenced

Central Drugs Standard Control Organization (CDSCO): The national regulatory body for pharmaceuticals and medical devices in India. India Medtronic Pvt. Ltd.: The local distributor of the affected medical device in India and responsible for the field safety corrective action. EEA Auto Suture Circular Stapler/ Loading unit with DST Series Technology (Staple): The medical device subject to the alert due to a potential defect. Medical Devices Rules, 2017: The regulatory framework governing medical devices in India, which includes provisions for field safety corrective actions and reporting requirements. M/s Covidien IIc: Legal Manufacturing Site of the device M/s Covidien: Actual Manufacturing Site of the device
Official Source Record View Original Source →
See Full Document Text
Central Drugs Standard Control Organization Directorate General of Health Services Ministry of Health and Family Welfare Government of India (Medical Devices and Diagnostics Division) Email: ddcimd-cdsco@nic.in Food & Drugs Administration Bhawan, Kotla Road, New Delhi. F.No.29/Misc/03/2021-DC (355) Date: 14th June 2022 MEDICAL DEVICE ALERT DEVICE EEA Auto Suture Circular Stapler/ Loading unit with DST Series Technology (Staple) BACKGROUND The DST Series™ EEA™ stapler is used throughout the alimentary tract for the creation of end-to end, end-to side, and side-to-side anastomoses in both open and laparoscopic surgeries. Distributed 25mm EEA Auto suture Circular Staplers with DST Series Technology, with model numbers EEA25, EEAXL25, EEA2535, and EEAXL2535, have the potential for the staple guide to not be securely attached to the instrument. This issue is related only to the 25mm EEA Auto suture Circular Staplers with DST Series Technology. No other Medtronic products or other sizes of EEA Auto suture Circular Staplers with DST Series Technology are affected by this issue. Reason for Recall  A staple guide not attached to the instrument could cause the component to disengage and if disengaged, could allow the device to transect tissue without forming staples. This could result in delay of treatment, extended hospital stays, unspecified tissue injury, unintended radiation exposure, unexpected medical intervention, foreign body in patient, failure to anastomose, and hemorrhage. Who May Be Affected  Patients going for surgical procedures with the DST series EEA stapler used throughout the alimentary tract for the creation of end to end, end-to side, and side-to-side anastomoses in both open and laparoscopic surgeries. Important Note: CDSCO have not received any complaints from the market on this issue. Page 1 of 2FURTHER DETAILS & CONTACTS M/s India Medtronic Pvt. Ltd, Gurugram, Haryana had issued a Field Safety Notice which is attached herewith this alert. M/s India Medtronic Pvt. Ltd. 4th Floor, Tower A & B SAS Tower Medanta The Medicity Complex Sector 38, Gurugram 122001 Haryana, India www.medtronic.co.in Tel +91-124-4709800 Fax +91-124-4206850 Page 2 of 2FIELD SAFETY CORRECTIVE ACTION NOTIFICATION (FSCA) FORM 1. Before filling this form, the reporter collects and collates the prescribed information in the form. 2. This form will serve as the reporting tool in lieu with the Medical Devices Rules, 2017. Fourth Schedule [See rule 20(2), 21(2), 34(2), 63(1) and 64(1)] Part II (ii) (b) and Appendix II for intimating, notifying CDSCO for any Field Safety Corrective Action (FSCA) in relation to medical device product recall and other corrective action. 3. A scanned signed copy of PDF version of this form is to be sent to CDSCO via email to dci.nic.in 4. Additional information that may be pertinent for the completion of this form can be provided as an attachment. 5. All the field safety notices will be published on the CDSCO website and the reporter holds the full responsibility for the information contained in the Field Safety Notification and reporter must indemnify CDSCO for all losses, claims, demands, liabilities, causes of action, expenses of any ki nd arising from CDSCO’s publication of the FSN. Primary Information  Type of Field Safety Corrective Product Recall 1. Action (FSCA)  Other Corrective actions Type of Report  Notification 2.  Preliminary Report  Final Report 10-May-2022 3. Date of Report (dd/mm/yy) 4. Reference Number (auto generated by system) Particulars of Reporters Latika Vats 1. Contact Person Name Director-Regulatory Affairs and Quality Assurance 2. Job Title +917227907498 3. Telephone Numbers rs.indiaregulatory@medtronic.com 4. Email Address Medtronic 5. Office Address India Medtronic Pvt Ltd, 4t Floor, Tower A & B, SAS Tower, Medanta The Medicity complex Sector 38, Gurugram 122001, Haryana India Same as above 6. Local Contact Details (if reporter not based in India)Device General Information EEA Auto Suture Circular Stapler/ Loading unit with DST Series 1. Device Name Technology (Staple) Accessories / Associated NA 2. Devices Affected The DST Series™ EEA™ stapler is used throughout the alimentary tract 3. Device Intended Use for the creation of end-to end, end-to side, and side-to-side anastomoses in both open and laparoscopic surgeries. Regulatory Details Other than India 1. Device Regulatory Status Is the device registered globally  Yes  No Is the device marketed globally  Yes  No If yes provide details: In India 1. Device Regulatory Status Is the device registered in India  Yes  No Is the device marketed in India  Yes  No If yes provide details : IMP/MD/2018/000215 Legal Manufacturing Site : M/s Covidien IIc, 15 Hampshire Street, 2. Manufacturer(s) and Contact Mansfield, MA 02048, Country: United States Telephone No.: 303-305- Details 2841 FAX: 303-305- 2212 E-Mail : Michael.Aymami@covidien.com Actual Manufacturing Site : M/s Covidien, Building 911-67, Sabanetas 3. Product License Holder / Local Industrial Park, Ponce, Puerto Rico 00731, Country: United States Authorized Representative Telephone No.: 787-259-6505 FAX: 787- 259-1485 E-Mail : carlos. Name & Address rodriguez@medtronic.com M/s India Medtronic Private Limited, Plot No 609 Survey/Shed-188 4. Importer(s) / Distributor(s) (part) Chamunda Compound,Kasheli Village, Dist Thane, Bhiwandi and Contact Details 421301 Maharashtra , Thane, Maharashtra (India) - 421301 Telephone No.: 22330747001 FAX: 22330747001 Impacted Device Information Please refer attachment#1 FA1245 1. Model Number Not applicable 2. Catalogue Number Not Applicable 3. Serial Number Please refer attachment#1 FA1245 4. Affected Lot / Batch Number NA 5. UDI Number NA 6. Accessories / Associated Devices AffectedDevice Related to FSCA Information 1. Number of affected Unit Manufactured in India Period : NA Imported into India- 2625 Period : Jun 2017 to Feb 2022 Supplied in India- 2408 Period : Jun 2017 to May 2022 Expected Shipment to India- NA Expected Date of Arrival: NA Please refer attachment#1 FA1245 2. Number of affected units supplied to each consignee 3. FSCA Strategy gk • A voluntary FCA will be implemented to communicate the issue to all consignees who have received affected product according to Medtronic records. • Consignees will be asked to confirm receipt of FCA notification. • Consignees, including Medtronic field representatives, will be asked to return all unused affected sold product within their possession. • Reconciliation of returned product will be managed per Product Hold Order 4. Did the FSCA arise due to an ☒ Yes  No adverse event ? 5. If yes, what is the category of ☐ Serious Public Health Threat adverse event ? ☐ Death ☒ Serious Injury ☐ Non-Serious Injury 6. Did this adverse event occur in ☒ Yes ☐ No India ? If Yes then adverse event Ref. No. & Summary : N/A Risk Summary and Acceptability 7. Evaluation of risk associated with affected device (Health The overall risk falls into Zone 1 and Zone 2 for the potential harms Hazard Evaluation Report) of failure to anastomose, unspecified tissue injury, hemorrhage/bleeding, delay to treatment/therapy, unexpected medical intervention, foreign body in patient, and unintended radiation exposure. The highest potential of harm is a severity of 4. The scoring of this IIA reflects the full risk of harm (severity of 4).8. Give reason & detail for FSCA (if other than the adverse Not Applicable event)Affected Device Details (e.g. device identifiers, lot/batch No.) listed in the FSCA Communication For Other than India Yes 1. Has the FSCA communication been sent to all consignees ? 13-May-22 2. Date of commencement of FSCA by product owner (dd/mm/yyy) 13-May-22 to 30-May-22 3. Date of commencement of FSCA (if applicable) Information Awaited 4. Countries to which FSCA has been reported (if any) 21-Jul-2023 5. Proposed date of completion of FSCA (if applicable) 6. Summary of root cause analysis CAPA2022-018332 was issued to investigate the root cause of the issue CAPA2022-018332 was issued to investigate the root cause of the issue 7. Summary of Corrective and Preventive Action (CAPA) For India Please refer attachment#1 FA1245 1. Affected device details 2. Has the FSCA communication ☒ Yes, Date Sent :  No been sent to all consignees ? (dd/mm/yyy) (dd/mm/yyy) Expected Date to be sent : 25-May-2022 13- May-2022 3. Date of commencement of FSCA by product owner (dd/mm/yyy) 25-May-2022 4. Date of commencement of FSCA in India (if applicable) Information Awaited 5. Countries to which FSCA has been reported (if any) 21-Jul-2023 6. Proposed date of completion of FSCA (if applicable)CAPA2022-018332 was issued to investigate the root cause of the issue 7. Summary of root cause analysis CAPA2022-018332 was issued to investigate the root cause of the issue. 8. Summary of Corrective and Preventive Action (CAPA) Change Notification (if applicable) No change in software, design or labelling 1. Type of change (software change, design change, labelling) 2. For software change, have any  Yes  No feature not related to FSCA incorporates If Yes then provide details : Other Information I attested that the information submitted is true and accurate and that I am authorized to submit this form in behalf of company. Signature : …………………………………………………. Name of reporting person : Latika Vats (Director-Regulatory Affairs and Quality Assurance) Date of Notification : ………………………………………………….

Continue your research